Skip to main content
Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1982 Jun;15(6):1062–1064. doi: 10.1128/jcm.15.6.1062-1064.1982

Frequency of Escherichia coli strains producing heat-labile toxin or heat-stable toxin or both in children with and without diarrhea in São Paulo.

M H Reis, B E Guth, T A Gomes, J Murahovschi, L R Trabulsi
PMCID: PMC272254  PMID: 7050145

Abstract

Enterotoxigenic Escherichia coli strains were isolated from 32 (13.4%) of 245 children with diarrhea and from 11 (11.4%) of 96 children of the control group. Strains producing heat-labile toxin were found more frequently in normal children than in children with diarrhea. Strains producing heat-stable toxin and both heat-labile and heat-stable toxins were isolated only from children with diarrhea. Association of these strains with diarrhea was highly significant as shown by statistical analysis. The O:H types and the colonization factors of strains producing heat-stable toxin and both heat-labile and heat-stable toxins are presented.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Dean A. G., Ching Y. C., Williams R. G., Harden L. B. Test for Escherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu. J Infect Dis. 1972 Apr;125(4):407–411. doi: 10.1093/infdis/125.4.407. [DOI] [PubMed] [Google Scholar]
  2. Donta S. T., Moon H. W., Whipp S. C. Detection of heat-labile Escherichia coli enterotoxin with the use of adrenal cells in tissue culture. Science. 1974 Jan 25;183(4122):334–336. doi: 10.1126/science.183.4122.334. [DOI] [PubMed] [Google Scholar]
  3. Donta S. T., Wallace R. B., Whipp S. C., Olarte J. Enterotoxigenic Escherichia coli and diarrheal disease in Mexican children. J Infect Dis. 1977 Mar;135(3):482–485. doi: 10.1093/infdis/135.3.482. [DOI] [PubMed] [Google Scholar]
  4. Echeverria P., Blacklow N. R., Vollet J. L., 3rd, Ulyangco C. V., Cukor G., Soriano V. B., DuPont H. L., Cross J. H., Orskov F., Orskov I. Reovirus-like agent and enterotoxigenic Escherichia coli infections in pediatric diarrhea in the Philippines. J Infect Dis. 1978 Sep;138(3):326–332. doi: 10.1093/infdis/138.3.326. [DOI] [PubMed] [Google Scholar]
  5. Echeverria P., Ho M. T., Blacklow N. R., Quinnan G., Portnoy B., Olson J. G., Conklin R., DuPont H. L., Cross J. H. Relative importance of viruses and bacteria in the etiology of pediatric diarrhea in Taiwan. J Infect Dis. 1977 Sep;136(3):383–390. doi: 10.1093/infdis/136.3.383. [DOI] [PubMed] [Google Scholar]
  6. Edelman R., Levine M. M. Acute diarrheal infections in infants I. Bacterial and viral causes. Hosp Pract. 1980 Jan;15(1):97–104. doi: 10.1080/21548331.1980.11946543. [DOI] [PubMed] [Google Scholar]
  7. Evans D. G., Evans D. J., Jr New surface-associated heat-labile colonization factor antigen (CFA/II) produced by enterotoxigenic Escherichia coli of serogroups O6 and O8. Infect Immun. 1978 Aug;21(2):638–647. doi: 10.1128/iai.21.2.638-647.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Evans D. G., Evans D. J., Jr, Pierce N. F. Differences in the response of rabbit small intestine to heat-labile and heat-stable enterotoxins of Escherichia coli. Infect Immun. 1973 Jun;7(6):873–880. doi: 10.1128/iai.7.6.873-880.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Evans D. G., Olarte J., DuPont H. L., Evans D. J., Jr, Galindo E., Portnoy B. L., Conklin R. H. Enteropathogens associated with pediatric diarrhea in Mexico City. J Pediatr. 1977 Jul;91(1):65–68. doi: 10.1016/s0022-3476(77)80446-0. [DOI] [PubMed] [Google Scholar]
  10. Evans D. G., Silver R. P., Evans D. J., Jr, Chase D. G., Gorbach S. L. Plasmid-controlled colonization factor associated with virulence in Esherichia coli enterotoxigenic for humans. Infect Immun. 1975 Sep;12(3):656–667. doi: 10.1128/iai.12.3.656-667.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Guerrant R. L., Moore R. A., Kirschenfeld P. M., Sande M. A. Role of toxigenic and invasive bacteria in acute diarrhea of childhood. N Engl J Med. 1975 Sep 18;293(12):567–572. doi: 10.1056/NEJM197509182931201. [DOI] [PubMed] [Google Scholar]
  12. Gurwith M. J., Williams T. W. Gastroenteritis in children: a two-year review in Manitoba. I. Etiology. J Infect Dis. 1977 Aug;136(2):239–247. doi: 10.1093/infdis/136.2.239. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Levine M. M., Rennels M. B., Daya V., Hughes T. P. Hemagglutination and colonization factors in enterotoxigenic and enteropathogenic Escherichia coli that cause diarrhea. J Infect Dis. 1980 Jun;141(6):733–737. doi: 10.1093/infdis/141.6.733. [DOI] [PubMed] [Google Scholar]
  14. Pickering L. K., Evans D. J., Jr, Muñoz O., DuPont H. L., Coello-Ramírez P., Vollet J. J., Conklin R. H., Olarte J., Kohl S. Prospective study of enteropathogens in children with diarrhea in Houston and Mexico. J Pediatr. 1978 Sep;93(3):383–388. doi: 10.1016/s0022-3476(78)81142-1. [DOI] [PubMed] [Google Scholar]
  15. Reis M. H., Heloiza M., Affonso T., Trabulsi L. R., Mazaitis A. J., Maas R., Maas W. K. Transfer of a CFA/I-ST plasmid promoted by a conjugative plasmid in a strain of Escherichia coli of serotype O128ac:H12. Infect Immun. 1980 Jul;29(1):140–143. doi: 10.1128/iai.29.1.140-143.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Reis M. H., Matos D. P., de Castro A. F., Toledo M. R., Trabulsi L. R. Relationship among enterotoxigenic phenotypes, serotypes, and sources of strains in enterotoxigenic Escherichia coli. Infect Immun. 1980 Apr;28(1):24–27. doi: 10.1128/iai.28.1.24-27.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Sebodo T., Soenarto Y., Rohde J. E., Ryan N. J., Taylor B. J., Luke R. J., Bishop R. F., Barnes G. L., Holmes I. H., Ruck B. J. Aetiology of diarrhoea in children aged less than two years in central Java. Lancet. 1977 Feb 26;1(8009):490–491. doi: 10.1016/s0140-6736(77)91984-5. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES