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. 1982 Sep;16(3):427–431. doi: 10.1128/jcm.16.3.427-431.1982

Staphylococcus saprophyticus as a cause of urinary tract infections.

T J Marrie, C Kwan, M A Noble, A West, L Duffield
PMCID: PMC272384  PMID: 6890071

Abstract

Our objectives in this study were to elucidate various aspects of the epidemiology of Staphylococcus saprophyticus. This organism was isolated from the midstream urine specimens of 7.5% of 145 college women with frequency and urgency of urination and dysuria, but from only 0.07% of 14,835 urine specimens from adult inpatients at the Victoria General Hospital. It was found to be part of the urethral flora of only 2% of healthy women. Other staphylococci which formed part of the urethral flora of 100 healthy women included S. epidermidis (59 women), S. hominis (15 women), S. haemolyticus (13 women), S. warneri (9 women), and S. aureus (6 women). Finally, we determined that resistance to the 5-micrograms novobiocin disk has a 93% positive predictive accuracy as a presumptive test for S. saprophyticus.

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Selected References

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  1. Anderson J. D., Clarke A. M., Anderson M. E., Isaac-Renton J. L., McLoughlin M. G. Urinary tract infections due to Staphylococcus saprophyticus biotype 3. Can Med Assoc J. 1981 Feb 15;124(4):415–418. [PMC free article] [PubMed] [Google Scholar]
  2. Bailey R. R. Significance of coagulase-negative Staphylococcus in urine. J Infect Dis. 1973 Feb;127(2):179–182. doi: 10.1093/infdis/127.2.179. [DOI] [PubMed] [Google Scholar]
  3. Colleen S., Hovelius B., Wieslander A., Mårdh P. A. Surface properties of Staphylococcus saprophyticus and Staphylococcus epidermidis as studied by adherence tests and two-polymer, aqueous phase systems. Acta Pathol Microbiol Scand B. 1979 Dec;87(6):321–328. doi: 10.1111/j.1699-0463.1979.tb02446.x. [DOI] [PubMed] [Google Scholar]
  4. Digranes A., Oeding P. Characterization of Micrococcaceae from the urinary tract. Acta Pathol Microbiol Scand B. 1975 Aug;83(4):373–381. doi: 10.1111/j.1699-0463.1975.tb00115.x. [DOI] [PubMed] [Google Scholar]
  5. Faller A., Schleifer K. H. Modified oxidase and benzidine tests for separation of staphylococci from micrococci. J Clin Microbiol. 1981 Jun;13(6):1031–1035. doi: 10.1128/jcm.13.6.1031-1035.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Gillespie W. A., Sellin M. A., Gill P., Stephens M., Tuckwell L. A., Hilton A. L. Urinary tract infection in young women, with special reference to Staphylococcus saprophyticus. J Clin Pathol. 1978 Apr;31(4):348–350. doi: 10.1136/jcp.31.4.348. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hovelius B., Mårdh P. A., Bygren P. Urinary tract infections caused by Staphylococcus saprophyticus: recurrences and complications. J Urol. 1979 Nov;122(5):645–647. doi: 10.1016/s0022-5347(17)56541-6. [DOI] [PubMed] [Google Scholar]
  8. Hovelius B., Thelin I., Mårdh P. A. Staphylococcus saprophyticus in the aetiology of nongonococcal urethritis. Br J Vener Dis. 1979 Oct;55(5):369–374. doi: 10.1136/sti.55.5.369. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Jordan P. A., Iravani A., Richard G. A., Baer H. Urinary tract infection caused by Staphylococcus saprophyticus. J Infect Dis. 1980 Oct;142(4):510–515. doi: 10.1093/infdis/142.4.510. [DOI] [PubMed] [Google Scholar]
  10. Kerr H. Urinary infection caused by Micrococcus subgroup 3. J Clin Pathol. 1973 Dec;26(12):918–920. doi: 10.1136/jcp.26.12.918. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Kloos W. E., Schleifer K. H. Simplified scheme for routine identification of human Staphylococcus species. J Clin Microbiol. 1975 Jan;1(1):82–88. doi: 10.1128/jcm.1.1.82-88.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Marrie T. J., Swantee C. A., Hartlen M. Aerobic and anaerobic urethral flora of healthy females in various physiological age groups and of females with urinary tract infections. J Clin Microbiol. 1980 Jun;11(6):654–659. doi: 10.1128/jcm.11.6.654-659.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Maskell R. Importance of coagulase-negative staphylococci as pathogens in the urinary tract. Lancet. 1974 Jun 8;1(7867):1155–1158. doi: 10.1016/s0140-6736(74)90634-5. [DOI] [PubMed] [Google Scholar]
  14. Meers P. D., Whyte W., Sandys G. Coagulase-negative staphylococci and micrococci in urinary tract infections. J Clin Pathol. 1975 Apr;28(4):270–273. doi: 10.1136/jcp.28.4.270. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Mårdh P. A., Colleen S., Hovelius B. Attachment of bacteria to exfoliated cells from the urogenital tract. Invest Urol. 1979 Mar;16(5):322–326. [PubMed] [Google Scholar]
  16. Pead L., Crump J., Maskell R. Staphylococci as urinary pathogens. J Clin Pathol. 1977 May;30(5):427–431. doi: 10.1136/jcp.30.5.427. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Sellin M., Cooke D. I., Gillespie W. A., Sylvester D. G., Anderson J. D. Micrococcal urinary-tract infections in young women. Lancet. 1975 Sep 27;2(7935):570–572. doi: 10.1016/s0140-6736(75)90166-x. [DOI] [PubMed] [Google Scholar]
  18. Shrestha T. L., Darrell J. H. Urinary infection with coagulase-negative staphylococci in a teaching hospital. J Clin Pathol. 1979 Mar;32(3):299–302. doi: 10.1136/jcp.32.3.299. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Stamey T. A., Timothy M., Millar M., Mihara G. Recurrent urinary infections in adult women. The role of introital enterobacteria. Calif Med. 1971 Jul;115(1):1–19. [PMC free article] [PubMed] [Google Scholar]
  20. Stamm W. E., Wagner K. F., Amsel R., Alexander E. R., Turck M., Counts G. W., Holmes K. K. Causes of the acute urethral syndrome in women. N Engl J Med. 1980 Aug 21;303(8):409–415. doi: 10.1056/NEJM198008213030801. [DOI] [PubMed] [Google Scholar]
  21. Walkey F. A., Judge T. G., Thompson J., Sarkari N. B. Incidence of urinary infection in the elderly. Scott Med J. 1967 Nov;12(11):411–414. doi: 10.1177/003693306701201106. [DOI] [PubMed] [Google Scholar]
  22. Wallmark G., Arremark I., Telander B. Staphylococcus saprophyticus: a frequent cause of acute urinary tract infection among female outpatients. J Infect Dis. 1978 Dec;138(6):791–797. doi: 10.1093/infdis/138.6.791. [DOI] [PubMed] [Google Scholar]

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