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. Author manuscript; available in PMC: 2009 Aug 14.
Published in final edited form as: Stroke. 2008 Apr 10;39(6):1869–1874. doi: 10.1161/STROKEAHA.107.506022

Table 3. Sensorimotor Function Assessments.

Tests Group Day 0 Day 1 Day 3 Day 7 Day 14
Neurological score median (25th to 75th percentiles) WT 0 1 (0.25–1) 1 (1–2) 1 (1–2) 1 (0.25–1)
Ngb-Tg 0 1 (1–2) 2 (1.5–2) 1 (0–1) 1 (0–1)
Rotorod test, % of day 0 WT 100 70.5±10.8 78.5±10.6 90.5±9.7 104.3±3.3
Ngb-Tg 100 68.7±12.8 78.1±10.9 84.5±17.4 110.7±2.5
Hanging wire median (25th to 75th percentiles) WT 5 (4.75–5) 2.5 (1–4) 3.5 (2–4.25) 4 (4–5) 4.5 (4–5)
Ngb-Tg 5 (4.5–5) 3 (1.5–3) 4 (2.5–4) 4 (3.5–4) 4 (4–5)
Foot fault test median (25th to 75th percentiles) WT 0 (0–1) 3 (0–5.75) 4 (0–5.25) 5 (4–5) 2 (1–2)
Ngb-Tg 1 (0–1.5) 2 (1–5) 4 (2–6) 4 (3.5–4.5) 1 (1–1.5)
Body weight, % of day 0 WT 100 91.7±0.57 82.1±1.21 81.8±3.04 91.3±1.54
Ngb-Tg 100 91.5±0.73 80.1±1.58 81.2±3.45 91.9±1.55

Sensorimotor deficits and body weight loss were assessed before (day 0) and at days 1, 3, 7, and 14 after transient (1-hour) focal cerebral ischemia. Results are expressed as median values and 25th to 75th percentiles for assessments of neurological score, hanging wire, and foot fault tests; and mean±SEM for assessments of Rotorod test and body weight loss. N=6 for Ngb-Tg and 7 for WT per group; 23- to 27-g male mice. In all assessments, there were no statistical significant differences between WT and Ngb-Tg groups.