Abstract
A method is described for the detection of immunoglobulin M (IgM) antibodies to Toxoplasma gondii by using latex particles coated with antigens of the organism. An excellent qualitative agreement was noted when the latex method was compared with other tests for the detection of IgM toxoplasma antibodies. The method is simple and inexpensive to perform and does not require the use of whole killed organisms or an enzyme conjugate.
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Selected References
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- Bradford M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976 May 7;72:248–254. doi: 10.1016/0003-2697(76)90527-3. [DOI] [PubMed] [Google Scholar]
- Desmonts G., Naot Y., Remington J. S. Immunoglobulin M-immunosorbent agglutination assay for diagnosis of infectious diseases: diagnosis of acute congenital and acquired Toxoplasma infections. J Clin Microbiol. 1981 Nov;14(5):486–491. doi: 10.1128/jcm.14.5.486-491.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Handman E., Remington J. S. Antibody responses to toxoplasma antigens in mice infected with strains of different virulence. Infect Immun. 1980 Jul;29(1):215–220. doi: 10.1128/iai.29.1.215-220.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Naot Y., Remington J. S. An enzyme-linked immunosorbent assay for detection of IgM antibodies to Toxoplasma gondii: use for diagnosis of acute acquired toxoplasmosis. J Infect Dis. 1980 Nov;142(5):757–766. doi: 10.1093/infdis/142.5.757. [DOI] [PubMed] [Google Scholar]
- Remington J. S., Bloomfield M. M., Russell E., Jr, Robinson W. S. The RNA of toxoplasma gondii. Proc Soc Exp Biol Med. 1970 Feb;133(2):623–626. doi: 10.3181/00379727-133-34531. [DOI] [PubMed] [Google Scholar]
