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. Author manuscript; available in PMC: 2009 Aug 17.
Published in final edited form as: J Addict Med. 2008;2(4):178–184. doi: 10.1097/ADM.0b013e3181878673

Daily Tobacco Smoking in Treatment-Seeking Pathological Gamblers: Clinical Correlates and Co-occurring Psychiatric Disorders

Jon E Grant 1, Suck Won Kim 1, Brian L Odlaug 1, Marc N Potenza 2
PMCID: PMC2727939  NIHMSID: NIHMS89343  PMID: 19690628

Abstract

Objectives

Tobacco smoking and pathological gambling (PG) frequently co-occur. Little is known, however, about the clinical correlates and co-occurring psychiatric disorders in treatment-seeking pathological gamblers with and without daily tobacco smoking.

Methods

Among a sample of 465 consecutive treatment-seeking subjects with current DSM-IV PG, those with daily tobacco smoking were compared to those without daily tobacco smoking on measures of gambling symptom severity (South Oaks Gambling Screen [SOGS] and the Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling [PG-YBOCS]), types of gambling, social and legal problems, and co-occurring disorders.

Results

Two hundred and nine (44.9%) of the 465 subjects with PG reported current daily tobacco smoking. Gamblers with daily tobacco smoking as compared to those without had higher SOGS scores, had more severe PG-YBOCS behavior scores, endorsed more DSM-IV PG criteria, lost more money gambling, and were more likely to engage in non-strategic gambling, and were less likely to have a co-occurring mood disorder. Gamblers with daily tobacco smoking and a current substance use disorder reported a greater percentage of income lost to gambling during the past year.

Conclusions

Daily tobacco smoking in PG is common and associated with multiple important clinical features including more severe gambling and financial problems. These findings suggest that pathological gamblers with daily tobacco smoking might need unique or enhanced treatment strategies.

Keywords: pathological gambling, nicotine, impulse control disorders, tobacco, addiction

INTRODUCTION

Pathological gambling (PG) is characterized by persistent and recurrent maladaptive patterns of gambling. PG is associated with impaired functioning, reduced quality of life, bankruptcy, divorce and suicide.1-4 Past-year adult prevalence rates for PG are estimated at 1%.5-6 PG frequently co-occurs with other psychiatric disorders, including nicotine dependence.5

Among US adults, 16.7% to 22.4% report daily tobacco use.7-8 Estimates of daily tobacco use among problem/pathological gamblers have varied from 41% to 69%.9-12 Previous research has suggested that tobacco use is associated with more severe gambling problems,13-14 depressive symptoms, and non-strategic forms of gambling.9 However, these investigations did not consistently study individuals with PG, utilize diagnostic assessments for PG or other psychiatric disorders, use clinician-based assessments of gambling severity, examine treatment-seeking populations, or consider the relationship with non-tobacco forms of substance abuse or dependence. As both PG and tobacco smoking are associated with other substance use disorders, considering the potential influence of other forms of substance abuse/dependence on the relationship between tobacco smoking and PG is important. Recognizing the associations between daily tobacco smoking and current gambling symptomatology among individuals seeking treatment for PG is important as tobacco use may have implications for the clinical course of PG. For example, a recent study using imaginal desensitization in the treatment of PG found that current tobacco use was the strongest predictor of relapse to gambling after response to psychotherapy.15

The goal of the present study was to clarify the association between daily tobacco smoking and gambling symptomatology using a large sample of individuals meeting DSM-IV criteria for current PG and seeking treatment for the disorder. Based on previous research,9, 13-14 we hypothesized that for PG subjects with and without other substance abuse/dependence: 1) daily tobacco smoking would be common; 2) daily tobacco smoking would be associated with worse gambling symptomatology; 3) daily tobacco smoking would be associated with non-strategic forms of gambling; and 4) daily tobacco smoking would be associated with mood disorders.

METHODS

Subjects

Participants included 465 adult outpatients aged ≥18 years meeting current (past-year) DSM-IV criteria for PG and seeking treatment for the condition. Participants were recruited over a 7-year period (2001-2007) by advertisements and referrals for a cognitive-behavioral therapy study, pharmacological studies, or for outpatient treatment at either a private or a public hospital. Recruitment methods have been described in detail previously15-19 and are described in brief below. Although each treatment study had specific exclusion/inclusion criteria, 15-19 subjects not meeting these criteria were offered treatment in an outpatient clinic and asked to be included in ongoing, naturalistic treatment studies of PG. Although the treatment studies excluded subjects with current psychotic disorders or lifetime bipolar disorder, all subjects who sought treatment and were excluded from treatment studies were offered treatment in an outpatient clinic and included in the database. Data are not available on how many subjects were excluded from treatment studies who then came to the outpatient clinic versus those who came to clinic for outpatient treatment without contacting us for a study. No inclusion/exclusion criteria applied to those subjects who were treated in the outpatient clinic. Of the 465 subjects included in this database, 253 (54.4%) were recruited from pharmacological studies, 76 (16.3%) were recruited from a psychotherapy study, and 136 (29.2%) were recruited from an outpatient clinic. Subjects were recruited from two geographical sites – a Midwest public university hospital (n=393; 84.5%) and an East coast private university hospital (n=72; 15.5%).

The investigation was conducted in accordance with the Declaration of Helsinki. The Institutional Review Boards of the University of Minnesota and Butler Hospital approved the studies and the consent statements. All study participants provided voluntary written informed consent.

Assessments

At the intake interview, raters assessed each subject using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I)20 and the Structured Clinical Interview for Pathological Gambling (SCI-PG), a valid and reliable diagnostic instrument.21

A detailed clinical examination was used to collect information on demographic and clinical features of PG. All subjects included in this analysis were drawn from states where multiple types of gambling (i.e. both strategic and non-strategic) were available. Financial information was collected with routine questions asking about money lost to gambling and financial effects of gambling.

PG symptom severity was assessed with three measures

Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling (PG-YBOCS)

The PG-YBOCS is a reliable and valid, 10-item, clinician-administered scale, reflecting gambling symptoms within the last seven days.22 The first five items of the PG-YBOCS comprise the gambling urge/thought subscale (time occupied with urges/thoughts; interference and distress due to urges/thoughts; resistance against and control over urges/thoughts), and items 6-10 comprise the gambling behavior subscale (time spent gambling and amount of gambling; interference and distress due to gambling; ability to resist and control gambling). Items are rated from 0 to 4, with higher scores reflecting greater severity, and total scores ranging from 0 to 40.

South Oaks Gambling Screen (SOGS)

The SOGS is a valid and reliable, 20-item, self-report screening instrument. The SOGS assesses gambling symptoms over a person’s lifetime.23 A score of 5 or more on the SOGS indicates probable PG.

Clinical Global Impression-Severity scale (CGI)

The CGI Severity scale is a reliable and valid, 7-item scale assessing severity of PG symptoms at the baseline visit. The scale ranges from 1 = “not ill at all” to 7 = “among the most severely ill.”24

All subjects were queried regarding tobacco use. Subjects were drawn from states which did not restrict smoking in the casinos. Although no formalized smoking assessment was used, all subjects were interviewed by two of the investigators (JEG or SWK) who asked if the person was a current user of tobacco, the form of tobacco, and the amount of tobacco use. Subjects who smoked tobacco daily for the past 12-months were categorized as “daily tobacco smokers.” All daily tobacco smokers reported smoking cigarettes and self-reported measures of cigarettes per day were collected.

Statistical analysis

The percentage of PG subjects who reported current (past 12 months) daily tobacco smoking was determined. Those PG subjects who smoked tobacco daily were compared to those without daily tobacco smoking on demographic and clinical variables. Differences between the two groups were examined using Pearson chi-square, Fisher’s exact, t-tests (two-tailed), or Mann-Whitney test. To investigate whether some observed differences between daily and non-daily tobacco users may be associated with current substance use disorders, the sample was stratified according to current substance use status. All comparison tests were two-tailed. A Bonferroni correction was used to correct for multiple comparions, yielding an alpha level of .004 to determine statistical significance. Although no data reached statistical significance using the Bonferroni correction, we highlight statistical differences at the .05 alpha level as these findings may have clinical significance.

RESULTS

Daily Tobacco Smoking and Sociodemographic Variables

465 adults (250 [53.8%] females; mean age = 47.6 ± 11.4 [range 19 78]) with DSM-IV PG participated in the studies. The majority of subjects were white, non-Hispanic (n=429; 92.3%). 143 (30.8%) subjects were single and 322 (69.2%) were married, divorced, separated, or widowed. 277 (59.6%) had at least some college education.

Of the 465 PG subjects, 209 (44.9%) (95%CI=40.4%-49.4%) reported current daily tobacco smoking. Subjects with daily tobacco use smoked a mean of 25.2 ± 13.4 [range 5 80] cigarettes per day. The daily tobacco smoking group did not significantly differ from those without daily tobacco smoking on demographic features (Table 1). Of the non-daily tobacco smokers, 107 (23.0%) were former smokers.

Table 1.

Demographics of 465 Pathological Gamblers with and without Current Daily Tobacco Smoking

All Pathological Gambling Subjects No Current Substance Use Disorder (n=355) Current Substance Use Disorders (n=110)

No Daily
Tobacco
Smoking
(n=256)
Daily
Tobacco
Smoking
(n=209)
Stat* df p-
value
No Daily
Tobacco
Smoking
(n=200)
Daily
Tobacco
Smoking
(n=155)
Stat* df p-
value
No Daily
Tobacco
Smoking
(n=56)
Daily
Tobacco
Smoking
(n=54)
Stat* df p-
value
Age, years 48.45 (11.8) [19-78] 46.8 (10.7) [20-72] 1.588t 463 .133 47.8 (12.0) [19-78] 47.0 (10.4) [20-72] .702t 353 .483 50.7(11.0) [25-74] 46.3(11.5) [20-68] 2.091t 108 .039
Marital, n (%)
Single 79 (30.9) 64 (30.6) 2.01c 1 .654 60 (30.0) 44 (28.4) .063c 1 .803 19 (33.9) 20 (37.0) .116c 1 .733
Married/Div./Widow 177(69.1) 145 (69.4) 140 (70.0) 111 (71.6) 37 (66.1) 34 (63.0)
Race, n (%)
Caucasian 238 (93.0) 191 (91.4) .908c 1 .341 189 (94.5) 145 (93.5) .419c 1 .518 49 (87.5) 46 (85.2) .791c 1 .374
Other 18 (7.0) 18 (8.6) 11(5.5) 10 (6.5) 7 (12.5) 8 (14.8)
Education, n (%)
High School or less 101 (39.5) 87 (41.6) 2.232c 1 .135 68 (34.0) 53 (34.2) 1.619c 1 .203 33 (58.9) 34 (63.0) .248c 1 .618
At least some college 155 (60.5) 122 (58.4) 132 (68.0) 102 (65.8) 23 (45.1) 20 (37.0)
Gender, n (%)
Female 135 (52.7) 115 (55.0) .254c 1 .614 115 (57.5) 92 (59.4) .136c 1 .712 20 (35.7) 23 (42.6) .546c 1 .460

All scores are Mean (± SD), [range] unless otherwise indicated;

*

Statistic: c = Chi-square; t = t-test

Gambling Severity

PG subjects with daily tobacco smoking were distinguished at p<0.05 from those without daily tobacco smoking group on money lost gambling during the past year ($21,243 vs. $14,738; z=-2.106; p=.035), financial difficulties secondary to gambling (80.9% compared 73.0%; χ2 =3.915; df=1; p=.048), SOGS scores (14.3 ± 3.3 vs. 13.1 ± 3.8; t=2.407; df=463; p=.017), PG-YBOCS behavior scores (10.3 ± 3.8 compared to 9.3 ± 4.0; t=2.068; df=463; p=.040), and DSM-IV PG criteria (8.1 ± 1.3 compared to 7.5 ± 1.6; t=2.351; df=463; p=.020). In all cases, PG subjects with daily tobacco smoking had mean values reflecting greater problem gambling severity.

Of the 465 PG subjects, 110 (23.7%) had a current substance use disorder. 94 (20.2%) had an alcohol use disorder and 32 (6.9%) had a drug use disorder (most commonly, cannabis use disorder and cocaine use disorder). When the subjects were grouped by current substance use disorders, PG subjects with current substance use disorders plus daily tobacco smoking were distinguished at p<0.05 from those with current substance use disorders but without daily tobacco smoking in terms of the percentage of income spent gambling in the past year (75% compared to 55%; z=-1.983; p=.047). For those PG subjects without current substance use disorders, daily smokers had higher SOGS scores (14.1 ± 3.3 vs. 13.0 ± 3.8; t=1.989; df=353; p=.048). No other differences were significant at the p<.05 level when stratifying the sample according to the presence or absence of current substance use disorders.

Types of Gambling Problems

PG subjects with daily tobacco smoking and no current substance use disorder were distinguished at p<0.05 from those without daily tobacco smoking and no current substance use disorder on the measure of non-strategic gambling problems. For those with no current substance use disorder, PG subjects with daily tobacco smoking more frequently reported problems with non-strategic gambling (86.5% compared 78.0%; χ2 =4.170; df=1; p=.041). This difference seemed largely attributable to slot machine and bingo gambling.

Psychiatric Comorbidity

Although rates of most Axis I co-occurring disorders did not significantly differ between groups, PG subjects with daily tobacco smoking and no current substance use disorder were significantly less likely to have a co-occurring mood disorder (18.7% vs. 30.5%; χ2 =6.414; df=1; p=.011) (Table 3). In those without a current substance use disorder, the groups of PG subjects with and without daily tobacco smoking were distinguished at p<0.05 in terms the rate of depressive disorder NOS but not by the presence of any anxiety or eating disorder (Table 3).

Table 3.

Co-Occurring Disorders in 465 Pathological Gamblers with and without Current Daily Tobacco Smoking Based on Current Substance Use Disorder Status

All Pathological Gambling Subjects No Current Substance Use Disorder (n=355) Current Substance Use Disorders (n=110)

Current (past
12 months)
Co-occurring
Disorder,
n (%)
No Daily
Tobacco
Smoking
(n=256)
Daily
Tobacco
Smoking
(n=209)
Stat* df p-
value
No Daily
Tobacco
Smoking
(n=200)
Daily
Tobacco
Smoking
(n=155)
Stat* df p-
value
No Daily
Tobacco
Smoking
(n=56)
Daily
Tobacco
Smoking
(n=54)
Stat* df p-
value
Any Mood Disorder 86 (33.6) 51 (24.4) 4.678c 1 .031 61 (30.5) 29 (18.7) 6.414c 1 .011 25 (44.6) 22 (40.7) .171c 1 .679
Major depressive d/o 36 (14.1) 25 (12.0) .446c 1 .504 22 (11.0) 13 (8.4) .671c 1 .413 14 (25.0) 12 (22.2) .118c 1 .732
Depressive disorder NOS 49 (19.1) 26 (12.4) 3.819c 1 .051 39 (19.5) 16 (10.3) .5618c 1 .018 10 (17.9) 10 (18.5) .008c 1 .928
Dysthymia 21 (8.2) 10 (4.8) f n/a .190 17 (8.5) 7 (4.5) 1.035c 1 .309 4 (7.1) 3 (5.6) f n/a .106
Any Anxiety Disorder 33 (12.9) 20 (9.6) 1.257c 1 .262 25 (12.5) 11 (7.1) 2.798c 1 .094 8 (14.3) 9 (16.7) .119c 1 .730
Any Eating Disorder 9 (3.5) 2 (1.0) 3.262c 1 .071 6 (3.0) 1 (0.6) f n/a .142 3 (5.4) 1 (1.9) f n/a .618
*

Statistic: c = Chi-square f = Fisher’s exact

DISCUSSION

This study is the first to examine a large group of treatment-seeking individuals with PG with respect to daily tobacco smoking. A broad range of self-report and clinician-based measures was used. In contrast to prior studies which either used only self-report measures of gambling14 or had smaller samples,13 this study allowed for a more complete assessment of gambling-related thoughts and behaviors and had the power to identify between-group differences related to smoking status. In addition, this is the first study to investigate the relationship between PG and tobacco smoking in a large clinical sample when stratifying the group according to presence or absence of a non-tobacco substance use disorder.

Hypothesis 1 (daily tobacco smoking will be common in PG)

In this study, we determined the frequency and clinical correlates of daily tobacco smoking in 465 treatment-seeking individuals with current DSM-IV PG. Consistent with our first hypothesis, close to one-half (45%) of PG subjects in this study reported current daily tobacco smoking. This percentage is two to three times higher than that found in the general population (16.7% to 22.4%)7-8 and consistent with frequencies found previously in problem and pathological gamblers (41% to 69%).9-14, 25

Hypothesis 2 (daily tobacco smoking will be associated with worse gambling symptomatology)

Consistent with previous studies14 and generally supportive of our second hypothesis, we found that daily tobacco smoking was associated with more severe gambling symptoms as determined by most measures. For example, the SOGS scores, as well as the percentage of gross income spent on gambling, were higher in those with daily nicotine use, but the PG-YBOCS behavior subscale, the CGI Severity scores, and the amount of time spent gambling did not differ significantly based on daily tobacco smoking. Some of these measures did, however, approach significance at p<0.05. These findings suggest an influence of tobacco smoking on gambling, particularly with respect to specific aspects. For example, between-group differences in PG-YBOCS measures of gambling behavior but not thoughts or urges suggests that impairments in behavioral control might be related to the co-occurrence of tobacco smoking and PG. This interpretation would suggest that treatment strategies enhancing behavioral control might be particularly helpful for targeting smoking cessation and excessive gambling in daily smoking pathological gamblers.

The association between smoking and gambling could be mediated in multiple, non-mutually exclusive manners. For example, individuals who smoke could be more likely to gamble through events related to tobacco smoking; e.g., purchasing of scratch-off lottery tickets when purchasing cigarettes. Alternatively, individuals who gamble might be more likely to smoke; e.g., if smoking is a cultural component of a gambling venue like a casino. A third possibility is that smoking may influence gambling through experiences of reward or pleasure that influence behavioral decision-making.26-27 A fourth possibility is that specific individuals (e.g., those who are more impulsive) may be predisposed to engage excessively in both smoking and gambling. Additional research is needed to clarify these possibilities and develop more effective treatment strategies for individuals with co-occurring PG and daily tobacco smoking.

Hypothesis 3 (daily tobacco smoking will be associated with non-strategic forms of gambling)

Consistent with prior research, 9 daily tobacco smoking was associated with non-strategic forms of problem gambling, particularly slot machine and bingo gambling. This association appeared particularly relevant to daily-tobacco-smoking PG subjects without another current substance use disorder, suggesting that the confluence of substance use disorders influence the pattern of gambling in which individuals with PG engage. Non-strategic forms of gambling typically occur in casinos, halls or other venues in which groups congregate. Public health concerns related to first- and second-hand smoke have led to recent restrictions on smoking within some but not all such venues. The potential impact that such restrictions have on gambling behaviors warrants investigation.

Hypothesis 4 (daily tobacco smoking will be associated with greater rates of mood disorders)

Contrary to our fourth hypothesis, PG subjects with daily tobacco smoking in this study were less likely meet criteria for a current mood disorder. This finding was observed within the group of PG subjects without a current non-tobacco substance use disorder but not in those with a current non-tobacco substance use disorder. Previous research in community samples has found higher estimates of most Axis I disorders, including major depressive disorder, in individuals with daily tobacco use as well as in pathological gamblers.5, 28-31 However, these studies typically did not stratify according to non-tobacco substance use disorder status. One previous study reported no significant between-group differences in ratings of depression in tobacco smoking and non-smoking problem gamblers in treatment.14 Our estimates of current mood disorders for the overall sample are consistent with rates found in other studies (16.1% - 20.0%).5,32 One explanation for the lower current rates of mood disorders found in tobacco smokers might be that lifetime rates of mood disorders were higher in those PG subjects with daily tobacco smoking but current rates reflect having sought treatment for mood disorders. Alternatively, this finding raises the question of whether tobacco smoking, in some PG subjects, may have an antidepressant effect. Causal factors underlying the relationship between mood, tobacco smoking and PG, particularly in relation to other substance use disorders, however, have yet to be identified and warrant further investigation.

Clinical Implications

The finding that pathological gamblers with daily tobacco smoking as compared to those without differed on multiple clinical measures is consistent with research on tobacco’s influence on other disorders and has significant implications for PG. Studies of cannabis use disorders demonstrate that untreated tobacco use results in fewer weeks of continuous abstinence.33-34 Additionally, some research suggests that treatment for tobacco use may benefit individuals who are attempting to maintain abstinence from alcohol.35 The implications of this research for PG are numerous. First, because gambling severity is associated with tobacco use, there is a significant need to understand better the nature of this relationship and enhance screening and prevention efforts related to tobacco use in individuals with PG. Second, daily tobacco smoking in PG was associated with more severe financial and possible legal difficulties secondary to gambling. Clinicians who screen for PG should be aware of treatment and counseling services that include financial and legal service. Third, in that types of problematic gambling appear more closely linked with tobacco smoking, prevention efforts targeting smoking cessation in gambling venues should consider assessing the public health implications related to PG.

Limitations and Strengths

This study has several limitations. First, daily tobacco smokers were considered together as a group. Additional information relating to severity and chronicity of tobacco smoking could be helpful in better understanding the relationship between smoking and gambling in PG. Second, non-daily tobacco smokers were considered together as a group. This group could include tobacco users (“chippers”, cigar or pipe smokers, users of chewable tobacco) who might not smoke on a daily basis, as well as prior daily tobacco smokers who are typically infrequent amongst problem gamblers.9 Future studies should delineate subsets of pathological gamblers according to a more complete battery of qualitative and quantitative set of smoking measures (e.g., a Fagerstrom Test for Nicotine Dependence36) in order to better characterize smoking-related clinical correlates. Third, since a treatment-seeking sample was used, it is unclear how generalizable the results are to non-treatment seeking individuals with PG. Fourth, lack of ethnic/racial diversity in our sample may suggest that these findings will not generalize to members of different ethnic and cultural groups. Fifth, the subjects were recruited over several years from a variety of venues without control groups taken from these various settings. Although this may have introduced some bias, this heterogeneity of place and time may actually reflect “real world” gambling pathology more closely. Sixth, smoking policy in public places such as casinos has been changing over the past decade and will likely continue to change in the near future. Monitoring the possible influences of these changes on the clinical correlates of tobacco smoking in individuals with PG will be important. Despite the limitations, the study has multiple strengths, including the large sample of treatment-seeking pathological gamblers and the use of both self-report and clinician-administered measures with strong psychometric properties and established norms.

Conclusions and Future Directions

The results provide further support that daily tobacco smoking in PG is common and has important clinical implications. Future research should investigate potential factors that may contribute to the etiology and pathophysiology of daily tobacco smoking and PG identify treatments specially tailored for individuals with both conditions.

Table 2.

Clinical Characteristics of 465 Pathological Gamblers with and without Current Daily Tobacco Smoking Based on Current Substance Use Disorder Status

All Pathological Gambling Subjects No Current Substance Use Disorder
(n=355)
Current Substance Use Disorders
(n=110)

No Daily
Tobacco
Smoking

(n=256)
Daily
Tobacco
Smoking

(n=209)
Stat* df p-
value
No Daily
Tobacco
Smoking

(n=200)
Daily
Tobacco
Smoking

(n=155)
Stat* df p-
value
No Daily
Tobacco
Smoking

(n=56)
Daily
Tobacco
Smoking

(n=54)
Stat* df p-
value
Hours spent gambling per week 13.2
(12.3) [0-90]
16.4
(13.1) [0-60]
-1.912z n/a .056 13.7
(9.9) [1-48]
18.3
(14.4) [0-60]
-1.764z n/a .078 11.7
(18.4) [0-90]
12.4
(8.5) [0-34]
-1.483z n/a .138
Total amount of money lost gambling during past year, dollars $14,738
($18,287) [$75-$120,000]
$21,243
($26,823) [$0-$190,000]
-2.106z n/a .035 15,718.4
(18,396) [150-12,000]
21,608.4
(27,884) [0-190,000]
-1.503z n/a .133 11,819.4
(17,850) [75-75,000]
20,386.1
(24,437) [10-100,000]
-1.431z n/a .153
Percentage of income lost to gambling during past year 55.7%
(72.2%)
76.8%
(158.3%)
-1.942z n/a .052 55.9
(72.3)
77.5
(176.8)
-1.052z n/a .293 55.0
(73.0)
74.7
(83.6)
-1.983z n/a .047
Legal Problems, n
(%)
Bankruptcy 42
(16.4)
45
(21.5)
1.987c 1 .159 30
(15.0)
27
(17.4)
.379c 1 .538 12
(21.4)
18
(33.3)
1.964c 1 .161
Any other legal issues 44
(17.2)
51
(24.2)
3.684c 1 .055 29
(14.5)
31
(20.0)
1.881c 1 .170 15
(26.8)
20
(37.0)
1.332c 1 .249
Other Problems, n
(%)
Financial 187
(73.0)
169
(80.9)
3.915c 1 .048 145
(72.5)
126
(81.3)
3.736c 1 .053 42
(75.0)
43
(79.6)
.336c 1 .562
Work 31
(12.1)
33
(15.8)
1.313c 1 .252 23
(11.5)
23
(14.8)
.863c 1 .353 8
(14.3)
10
(18.5)
.360c 1 .549
Housing 26
(10.2)
30
(14.3)
1.914c 1 .167 19
(9.5)
18
(11.6)
.418c 1 .518 7
(12.5)
12
(22.2)
1.818c 1 .177
Number of DSM-IV Criteria 7.5
(1.6) [5-10]
8.1
(1.3) [5-10]
2.351t 463 .020 7.5
(1.6) [5-10]
8.0
(1.4) [5-10]
1.589t 353 .115 7.6
(1.9) [5-10]
8.3
(1.1) [6-10]
1.503t 108 .144
South Oaks Gambling Screen 13.1
(3.8) [1-19]
14.3
(3.3) [5-20]
2.407t 463 .017 13.0
(3.8) [5-19]
14.1
(3.3) [6-19]
1.989t 353 .048 13.4
(3.6) [7-19]
14.9
(3.5) [5-20]
1.372t 108 .177
Clinical Global Impression Severity score 4.7
(.83) [2-7]
4.9
(.93) [0-7]
1.782t 463 .076 4.7
(0.8) [2-7]
4.8
(0.9) [0-7]
.888t 268 .375 4.6
(0.9) [3-7]
5.0
(0.9) [3-7]
1.947t 108 .054
PG-YBOCS total score 19.4
(5.4) [5-40]
20.6
(5.6) [9-35]
1.863t 463 .063 19.5
(5.2) [5-40]
20.8
(5.7) [9-35]
1.695t 268 .092 19.1
(6.1) [9-33]
20.2
(5.4) [10-33]
.782t 98 .437
PG-YBOCS Urge score 9.0
(3.2) [2-20]
9.1
(3.4) [2-19]
.354t 463 .724 9.0
(3.1) [2-20]
9.3
(3.4) [4-19]
.804t 268 .422 9.1
(3.7) [3-20]
8.7
(3.3) [2-19]
-.531t 98 .597
PG-YBOCS Behavior score 9.3
(4.0) [0-20]
10.3
(3.8) [0-19]
2.068t 463 .040 9.5
(3.8) [0-20]
10.4
(3.7) [0-19]
1.719t 268 .087 8.8
(4.4) [1-17]
10.1
(4.1) [4-18]
1.205t 98 .232
Types of Problem Gambling, n
(%)
Any Strategic 133
(52.0)
107
(51.2)
.026c 1 .871 107
(53.5)
76
(49.0)
.698c 1 .403 26
(46.4)
31
(57.4)
1.327c 1 .249
Any Non-strategic 203
(79.3)
181
(86.6)
4.270c 1 .039 156
(78.0)
134
(86.5)
4.170c 1 .041 47
(83.9)
47
(87.0)
.214c 1 .644
 Slots 168
(65.6)
159
(76.1)
6.022c 1 .014 130
(65.0)
121
(78.1)
7.196c 1 .007 38
(67.9)
38
(70.4)
.081c 1 .776
 Lottery 64
(25.0)
57
(27.3)
.309c 1 .578 48
(24.0)
50
(32.3)
2.980c 1 .084 16
(28.6)
7
(13.0)
4.050c 1 .044
 Pull tabs 22
(8.6)
25
(12.0)
1.436c 1 .231 16
(8.0)
16
(10.3)
.574c 1 .449 6
(10.7)
9
(16.7)
.827c 1 .363
 Bingo 33
(12.9)
41
(19.6)
3.891c 1 .049 29
(14.5)
39
(25.2)
6.409c 1 .011 4
(7.1)
2
(3.7)
f n/a .679
 Keno 8
(3.1)
4
(1.9)
.671c 1 .413 6
(3.0)
3
(1.9)
.400c 1 .527 2
(3.6)
1
(1.9)
f n/a 1.00
*

Statistic: c = Chi-square t = t-test f = Fisher’s exact z = Mann-Whitney

All scores are Mean (± SD), [range] unless otherwise indicated;

PG-YBOCS=Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling

Acknowledgments

Sources of Support: This research was supported in part by an NIMH Career Development Award (K23 MH069754-01A1) (JEG), a grant from NIMH (R21-MH065920) (SWK), a grant from NIDA (R01 DA019039) (MNP), a grant from NIAAA (RL1 AA017539) (MNP), the VA VISN1 MIRECC (MNP), and unrestricted educational grants from GlaxoSmithKline, Forest Pharmaceuticals, Somaxon Pharmaceuticals, and BioTie Therapies.

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