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. 2009 Aug 21;136(18):3173–3183. doi: 10.1242/dev.028902

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Fig. 7. — The Slit/Robo pathway is altered in the pharyngeal region of Tbx1 and Gbx2 mutant embryos. (A-I) ISH for Slit2 in wt (A,C,E,G) and mutant (B,D,F,H,I) E8.75 mouse embryos. Yellow and white arrows indicate downregulation or normal expression of Slit2, respectively. (J-N) A decreased number of migrating Robo1-positive cNCCs was detected in E9.5 Gbx2^-/- embryos (J) and in the caudal PAs of E10.5 Gbx2-PSE, Tbx1-PSE (Tbx1^flox/-;AP2α^Cre/+) and Tbx1^-/- embryos (yellow arrow and bracketed region in L,M,N) as compared with wt (K).