Skip to main content
PMC home page
Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1979 Mar;9(3):409–412. doi: 10.1128/jcm.9.3.409-412.1979

Biochemical characteristics of 130 recent isolates from Haemophilus influenzae meningitis.

M Kilian, I Sørensen, W Frederiksen
PMCID: PMC273039  PMID: 313403

Abstract

A total of 130 Haemophilus strains, comprising virtually all isolates from Danish and Norwegian cases of Haemophilus meningitis occurring in the period from October 1975 through September 1976, were examined by biochemical and serological means. All isolates were identified as H. influenzae and, except for one noncapsulated strain, possessed a capsule of serotype b. The vast majority of strains (93%) belonged to biotype I, which, in contrast to biotypes II and III, is rarely encountered as a commensal of the upper respiratory tract. This finding is a strong incentive for studies of possible additional virulence factors associated with biotype I organisms. The results are discussed in the light of North American reports, which have suggested changes in the etiology of Haemophilus meningitis.

Full text

PDF
409

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BIBERSTEIN E. L., MINI P. D., GILLS M. G. ACTION OF HAEMOPHILUS CULTURES ON DELTA-AMINOLEVULINIC ACID. J Bacteriol. 1963 Oct;86:814–819. doi: 10.1128/jb.86.4.814-819.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bachman D. S. Hemophilus meningitis: comparison of H. influenzae and H. parainfluenzae. Pediatrics. 1975 Apr;55(4):526–530. [PubMed] [Google Scholar]
  3. Barnshaw J. A., Phillips C. F. Haemophilus parainfluenzae meningitis in a 4-year-old boy. Pediatrics. 1970 May;45(5):856–857. [PubMed] [Google Scholar]
  4. CLARKE P. H., COWAN S. T. Biochemical methods for bacteriology. J Gen Microbiol. 1952 Feb;6(1-2):187–197. doi: 10.1099/00221287-6-1-2-187. [DOI] [PubMed] [Google Scholar]
  5. Gullekson E. H., Dumoff M. Haemophilus parainfluenzae meningitis in a newborn. JAMA. 1966 Dec 12;198(11):1221–1221. [PubMed] [Google Scholar]
  6. Hable K. A., Logan G. B., Washington J. A., 2nd Three Hemophilus species. Pathogenic activity. Am J Dis Child. 1971 Jan;121(1):35–37. doi: 10.1001/archpedi.1971.02100120071008. [DOI] [PubMed] [Google Scholar]
  7. Holt R. N., Taylor C. D., Schneider H. J., Hallock J. A. Three cases of Hemophilus parainfluenzae meningitis. Clin Pediatr (Phila) 1974 Aug;13(8):666–668. doi: 10.1177/000992287401300810. [DOI] [PubMed] [Google Scholar]
  8. Kaufman S. R., Hambly F., Dyke J. W., Gordon R. C. Hemophilus parainfluenzae meningitis. Clin Pediatr (Phila) 1974 Aug;13(8):661–663. doi: 10.1177/000992287401300809. [DOI] [PubMed] [Google Scholar]
  9. Kilian M. A rapid method for the differentiation of Haemophilus strains. The porphyrin test;. Acta Pathol Microbiol Scand B Microbiol Immunol. 1974 Dec;82(6):835–842. doi: 10.1111/j.1699-0463.1974.tb02381.x. [DOI] [PubMed] [Google Scholar]
  10. Kilian M. A taxonomic study of the genus Haemophilus, with the proposal of a new species. J Gen Microbiol. 1976 Mar;93(1):9–62. doi: 10.1099/00221287-93-1-9. [DOI] [PubMed] [Google Scholar]
  11. Kilian M., Schiott C. R. Haemophili and related bacteria in the human oral cavity. Arch Oral Biol. 1975 Dec;20(12):791–796. doi: 10.1016/0003-9969(75)90055-2. [DOI] [PubMed] [Google Scholar]
  12. Krishnaswami R., Schwartz J., Boodish W. Pathogenicity of H. parainfluenzae. Pediatrics. 1972 Sep;50(3):498–499. [PubMed] [Google Scholar]
  13. Lynn D. J., Kane J. G., Parker R. H. Haemophilus parainfluenzae and influenzae endocarditis: a review of forty cases. Medicine (Baltimore) 1977 Mar;56(2):115–128. doi: 10.1097/00005792-197703000-00003. [DOI] [PubMed] [Google Scholar]
  14. McGowan J. E., Jr, Klein J. O., Bratton L., Barnes M. W., Finland M. Meningitis and bacteremia due to Haemophilus influenzae: occurrence and mortality at Boston City Hospital in 12 selected years, 1935-1972. J Infect Dis. 1974 Aug;130(2):119–124. doi: 10.1093/infdis/130.2.119. [DOI] [PubMed] [Google Scholar]
  15. MØLLER V. Activity determination of amino acid decarboxylases in Enterobacteriaceae. Acta Pathol Microbiol Scand. 1954;34(2):102–114. doi: 10.1111/j.1699-0463.1954.tb00808.x. [DOI] [PubMed] [Google Scholar]
  16. Peltola H., Käyhty H., Sivonen A., Mäkelä H. Haemophilus influenzae type b capsular polysaccharide vaccine in children: a double-blind field study of 100,000 vaccinees 3 months to 5 years of age in Finland. Pediatrics. 1977 Nov;60(5):730–737. [PubMed] [Google Scholar]
  17. Wort A. J. Hemophilus parainfluenzae meningitis. Can Med Assoc J. 1975 Mar 8;112(5):606–607. [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES