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. 1979 Oct;10(4):404–408. doi: 10.1128/jcm.10.4.404-408.1979

Serological grouping of meningococci and encapsulated Haemophilus influenzae strains by latex agglutination.

M Leinonen, A Sivonen
PMCID: PMC273187  PMID: 118981

Abstract

The latex agglutination method, utilizing antibody-coated latex particles, was adapted for serogrouping of Neisseria meningitidis and serotyping of encapsulated Haemophilus influenzae strains from agar plates. It was found to give more clear-cut results than conventional slide agglutination. A 100% agreement with the antiserum agar method was found for all strains isolated from blood or cerebrospinal fluid. Many meningococcal strains from nasopharyngeal carriers are autoagglutinable, but some of these gave a positive reaction with the group B latex reagent, although they were negative by the antiserum agar method. The latex agglutination method has several advantages over others: the lack of autoagglutination, easy performance, easy interpretation, and very low consumption of antisera.

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Selected References

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