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. 1980 May;11(5):474–478. doi: 10.1128/jcm.11.5.474-478.1980

Seroepidemiology of clinical isolates of Klebsiella in Connecticut.

E A Blanchette, S J Rubin
PMCID: PMC273435  PMID: 7381012

Abstract

The distribution of capsular serotypes of 200 clinical isolates of Klebsiella pneumoniae and Klebsiella oxytoca from four Connecticut hospitals was determined. Serotyping was done by an indirect fluorescent-antibody technique. Hospitals included three community hospitals from the Hartford area and one university hospital in New Haven. During the test period, epidemiological surveillance did not detect any nosocomial epidemic involving Klebsiella species. Ninety-two percent of the isolates were typable. Of the 72 possible serotypes, 62 were represented among these strains. Forty-two percent of the typable strains were distributed among 10 serotypes. The predominant serotypes were types 31, 22, and 18 representing 19% of the typable strains (8, 6, and 5%, respectively). No one particular serotype was associated exclusively with a specific site of infection.

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Selected References

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  1. Adler J. L., Shulman J. A., Terry P. M., Feldman D. B., Skaliy P. Nosocomial colonization with kanamycin-resistant Klebsiella pneumoniae, types 2 and 11, in a premature nursery. J Pediatr. 1970 Sep;77(3):376–385. doi: 10.1016/s0022-3476(70)80004-x. [DOI] [PubMed] [Google Scholar]
  2. Casewell M. W., Dalton M. T., Webster M., Phillips I. Gentamicin-resistant Klebsiella aerogenes in a urological ward. Lancet. 1977 Aug 27;2(8035):444–446. doi: 10.1016/s0140-6736(77)90621-3. [DOI] [PubMed] [Google Scholar]
  3. Cichon M. J., Craig C. P., Sargent J., Brauner L. Nosocomial Klebsiella infections in an intensive care nursery. South Med J. 1977 Jan;70(1):33–35. doi: 10.1097/00007611-197701000-00016. [DOI] [PubMed] [Google Scholar]
  4. Dans P. E., Barrett F. F., Casey J. I., Finland M. Klebsiella-Enterobacter at Boston City Hospital, 1967. Arch Intern Med. 1970 Jan;125(1):94–101. [PubMed] [Google Scholar]
  5. Davis T. J., Matsen J. M. Prevalence and characteristics of Klebsiella species: relation to association with a hospital environment. J Infect Dis. 1974 Oct;130(4):402–405. doi: 10.1093/infdis/130.4.402. [DOI] [PubMed] [Google Scholar]
  6. EISENBERG G. M., O'LOUGHLIN J. M., FLIPPIN H. F. Distribution and in vitro antibiotic susceptibility of Klebsiella (Kauffman). J Lab Clin Med. 1954 May;43(5):707–712. [PubMed] [Google Scholar]
  7. Eickhoff T. C., Steinhauer B. W., Finland M. The Klebsiella-Enterobacter-Serratia division. Biochemical and serologic characteristics and susceptibility to antibiotics. Ann Intern Med. 1966 Dec;65(6):1163–1179. doi: 10.7326/0003-4819-65-6-1163. [DOI] [PubMed] [Google Scholar]
  8. Finland M. Nosocomial epidemics seriatim. Multidrug-resistant bacteria and R factors. Arch Intern Med. 1977 May;137(5):585–587. doi: 10.1001/archinte.137.5.585. [DOI] [PubMed] [Google Scholar]
  9. Gerding D. N., Buxton A. E., Hughes R. A., Cleary P. P., Arbaczawski J., Stamm W. E. Nosocomial multiply resistant Klebsiella pneumoniae: epidemiology of an outbreak of apparent index case origin. Antimicrob Agents Chemother. 1979 Apr;15(4):608–615. doi: 10.1128/aac.15.4.608. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hable K. A., Matsen J. M., Wheeler D. J., Hunt C. E., Quie P. G. Klebsiella type 33 septicemia in an infant intensive care unit. J Pediatr. 1972 Jun;80(6):920–924. doi: 10.1016/s0022-3476(72)80002-7. [DOI] [PubMed] [Google Scholar]
  11. Hill H. R., Hunt C. E., Matsen J. M. Nosocomial colonization with Klebsiella, type 26, in a neonatal intensive-care unit associated with an outbreak of sepsis, meningitis, and necrotizing enterocolitis. J Pediatr. 1974 Sep;85(3):415–419. doi: 10.1016/s0022-3476(74)80133-2. [DOI] [PubMed] [Google Scholar]
  12. Johanson W. G., Pierce A. K., Sanford J. P. Changing pharyngeal bacterial flora of hospitalized patients. Emergence of gram-negative bacilli. N Engl J Med. 1969 Nov 20;281(21):1137–1140. doi: 10.1056/NEJM196911202812101. [DOI] [PubMed] [Google Scholar]
  13. Martin W. J., Yu P. K., Washington J. A., 2nd Epidemiologic significance of Klebsiella pneumoniae. A 3-month study. Mayo Clin Proc. 1971 Dec;46(12):785–793. [PubMed] [Google Scholar]
  14. Matsen J. M., Spindler J. A., Blosser R. O. Characterization of Klebsiella isolates from natural receiving waters and comparison with human isolates. Appl Microbiol. 1974 Oct;28(4):672–678. doi: 10.1128/am.28.4.672-678.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Montgomerie J. Z. Epidemiology of Klebsiella and hospital-associated infections. Rev Infect Dis. 1979 Sep-Oct;1(5):736–753. doi: 10.1093/clinids/1.5.736. [DOI] [PubMed] [Google Scholar]
  16. Murcia A., Rubin S. J. Reproducibility of an indirect immunofluorescent-antibody technique for capsular serotyping of Klebsiella pneumoniae. J Clin Microbiol. 1979 Feb;9(2):208–213. doi: 10.1128/jcm.9.2.208-213.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Rennie R. P., Duncan I. B. Combined biochemical and serological typing of clinical isolates of Klebsiella. Appl Microbiol. 1974 Oct;28(4):534–539. doi: 10.1128/am.28.4.534-539.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Rennie R. P., Duncan I. B. Emergence of gentamicin-resistant Klebsiella in a general hospital. Antimicrob Agents Chemother. 1977 Feb;11(2):179–184. doi: 10.1128/aac.11.2.179. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Riser E., Noone P., Bonnet M. L. A new serotyping method for Klebsiella species: evaluation of the technique. J Clin Pathol. 1976 Apr;29(4):305–308. doi: 10.1136/jcp.29.4.305. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Riser E., Noone P., Poulton T. A. A new serotyping method for Klebsiella species: development of the technique. J Clin Pathol. 1976 Apr;29(4):296–304. doi: 10.1136/jcp.29.4.296. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Riser E., Noone P., Thompson R. E. The use of a fluorescence typing method in an epidemiological study of Klebsiella infection in a London hospital. J Hyg (Lond) 1978 Feb;80(1):43–56. doi: 10.1017/s0022172400053389. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Ross B. S., Peter G., Dempsey J. M., Oh W. Klebsiella pneumoniae nosocomial epidemic in an intensive care nursery due to contaminated intravenous fluid. Am J Dis Child. 1977 Jun;131(6):712–712. doi: 10.1001/archpedi.1977.02120190106026. [DOI] [PubMed] [Google Scholar]
  23. Rubin S. J., Brock S., Chamberland M., Lyons R. W. Combined serotyping and biotyping of Serratia marcescens. J Clin Microbiol. 1976 Jun;3(6):582–585. doi: 10.1128/jcm.3.6.582-585.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Thiemke W. A., Nathan D. M. Simultaneous nosocomial outbreaks caused by multiply resistant Klebsiella pneumoniae types 2 and 30. J Clin Microbiol. 1978 Dec;8(6):769–771. doi: 10.1128/jcm.8.6.769-771.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Thomas F. E., Jackson R. T., Melly A., Alford R. H. Sequential hospitalwide outbreaks of resistant Serratia and Klebsiella infections. Arch Intern Med. 1977 May;137(5):581–584. [PubMed] [Google Scholar]
  26. Valenti W. M., Trudell R. G., Bentley D. W. Factors predisposing to oropharyngeal colonization with gram-negative bacilli in the aged. N Engl J Med. 1978 May 18;298(20):1108–1111. doi: 10.1056/NEJM197805182982002. [DOI] [PubMed] [Google Scholar]
  27. WEIL A. J., BENJAMINSON M. A., DEGUZMAN B. C. THE KLEBSIELLA-AEROBACTER-SERRATIA DIVISION: ITS ROLE IN COMMON INFECTIONS OF MAN. Trans N Y Acad Sci. 1964 Nov;27:65–72. doi: 10.1111/j.2164-0947.1964.tb03487.x. [DOI] [PubMed] [Google Scholar]
  28. Weil A. J., Ramchand S., Arias M. E. Nosocomial infection with Klebsiella type 25. N Engl J Med. 1966 Jul 7;275(1):17–22. doi: 10.1056/NEJM196607072750104. [DOI] [PubMed] [Google Scholar]

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