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. 1980 Oct;12(4):493–497. doi: 10.1128/jcm.12.4.493-497.1980

Enzyme-linked immunosorbent assay for detection of antibody in volunteers experimentally infected with human coronavirus strain 229 E.

C A Kraaijeveld, S E Reed, M R Macnaughton
PMCID: PMC273622  PMID: 6252244

Abstract

An enzyme-linked immunosorbent assay was developed for detecting antibody rises to human coronavirus strain 229E and related strains in paired sera from infected volunteers. There was a close correlation between development of colds infected volunteers. There was a close correlation between development of colds and significant antibody rises detected by the enzyme-linked immunosorbent assay. Furthermore, the assay was more sensitive than a neutralization assay. This enzyme-linked immunosorbent assay is an easy, accurate, and sensitive assay for measuring significant antibody rises to human coronavirus strain 229E group viruses, and it could be useful in the clinical diagnosis of these infections.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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