Table 4.
Endoscopists' assessment of quality of bowel preparation. Values are numbers (percentages) of participants unless stated otherwise
| Total
|
Welwyn Garden City
|
Leicester
|
P value* | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Enema | Picolax | Difference in % (95% CI) | Enema | Picolax | Enema | Picolax | ||||
| No who used preparation at home | 635 | 584 | 260 | 241 | 375 | 343 | ||||
| Complete examinations (reaching descending colon or beyond) | 527 (83) | 445 (76) | 7 (2 to 11) | 226 (87) | 192 (80) | 301 (80) | 253 (74) | 0.53 | ||
| Incomplete examinations due to poor bowel preparation | 47 (7) | 59 (10) | −3 (−6 to 0) | 19 (7) | 21 (9) | 28 (7) | 38 (11) | 0.56 | ||
| Quality of bowel preparation: | ||||||||||
| Excellent | 359 (57) | 229 (39) | P<0.001 for trend | 115 (44) | 71 (29) | 244 (65) | 158 (46) | |||
| Good | 122 (19) | 153 (26) | 82 (32) | 92 (38) | 40 (11) | 61 (18) | ||||
| Adequate | 64 (10) | 96 (16) | 32 (12) | 52 (22) | 32 (9) | 44 (13) | ||||
| Poor | 62 (10) | 92 (16) | 17 (7) | 22 (9) | 45 (12) | 70 (20) | ||||
| Not recorded | 27 (4) | 14 (2) | 13 (5) | 4 (2) | 14 (4) | 10 (3) | ||||
| Mean % mucosa visible† (No of patients) at: | ||||||||||
| 0-15 cm | 95 (593) | 91 (552) | 4 (3 to 6) | 94 (244) | 92 (229) | 96 (349) | 91 (323) | |||
| 16-30 cm | 92 (591) | 87 (553) | 5 (3 to 8) | 91 (244) | 87 (230) | 93 (347) | 87 (323) | |||
| 31-45 cm | 88 (509) | 82 (469) | 6 (2 to 10) | 87 (230) | 82 (210) | 89 (279) | 82 (259) | |||
| 46-60 cm | 70 (136) | 60 (138) | 10 (−1 to 20) | 70 (57) | 72 (63) | 70 (79) | 51 (75) | |||
| Duration of examination (min)‡ | 4.9 | 5.4 | — | 4.3 | 5.0 | 5.2 | 5.6 | |||
| Yield at flexible sigmoidoscopy: | ||||||||||
| Polyps | 145 (23) | 122 (21) | 2 (−3 to 7) | 55 (21) | 52 (22) | 90 (24) | 70 (20) | 0.42 | ||
| Adenoma | 57 (9) | 55 (9) | 0 (−4 to 3) | 27 (10) | 27 (11) | 30 (8) | 28 (8) | 0.88 | ||
| Cancer | 5 (1) | 2 (0) | 0.5 (−0.4 to 1.3) | 3 (1) | 1 (0) | 2 (1) | 1 (0) | 0.80 | ||
| Total No of polyps | 206 | 188 | 0.5 (0.5 to 0.6)§ | 84 | 79 | 122 | 109 | |||
*
Significance test for homogeneity of bowel preparation effect between Welwyn Garden City and Leicester.
†
Includes examinations in which the scope was advanced to beyond the section of the bowel assessed unless the examination was terminated because of poor bowel preparation, in which case the % visible was set at 0% for subsequent sections.
‡
Excluding examinations stopped due to inadequate bowel preparation and participants in whom polyps or cancer were detected.
§
Binomial test for equality in two arms.