Abstract
We observed that the pH of positive blood culture broths was significantly lower than that of negative broths. However, significantly pH changes were generally not observed for subculture-positive, macroscopically negative blood culture broths. Therefore, although the pH of most positive blood culture broths was reduced significantly, this change was generally not useful for the early detection of positive cultures.
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Selected References
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- Beaman K. D., Kasten B. L., Corlett C. L., Gavan T. L. Effects of blood on blood culture medium. J Clin Microbiol. 1979 Oct;10(4):488–491. doi: 10.1128/jcm.10.4.488-491.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Blazevic D. J., Stemper J. E., Matsen J. M. Comparison of macroscopic examination, routine gram stains, and routine subcultures in the initial detection of positive blood cultures. Appl Microbiol. 1974 Mar;27(3):537–539. doi: 10.1128/am.27.3.537-539.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Brooks K., Sodeman T. Rapid detection of bacteremia by a radiometric system. A clinical evaluation. Am J Clin Pathol. 1974 Jun;61(6):859–866. doi: 10.1093/ajcp/61.6.859. [DOI] [PubMed] [Google Scholar]
- Cady P., Dufour S. W., Lawless P., Nunke B., Kraeger S. J. Impedimetric screening for bacteriuria. J Clin Microbiol. 1978 Mar;7(3):273–278. doi: 10.1128/jcm.7.3.273-278.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DeLand F., Wagner H. N., Jr Automated radiometric detection of bacterial growth in blood cultures. J Lab Clin Med. 1970 Mar;75(3):529–534. [PubMed] [Google Scholar]
- McCarthy L. R., Senne J. E. Evaluation of acridine orange stain for detection of microorganisms in blood cultures. J Clin Microbiol. 1980 Mar;11(3):281–285. doi: 10.1128/jcm.11.3.281-285.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Murray P. R., Sondag J. E. Evaluation of routine subcultures of macroscopically negative blood cultures for detection of anaerobes. J Clin Microbiol. 1978 Oct;8(4):427–430. doi: 10.1128/jcm.8.4.427-430.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ripa K. T., Mårdh P. A., Hovelius B., Ljungholm K. Microcalorimetry as a tool for evaluation of blood culture media. J Clin Microbiol. 1977 Apr;5(4):393–396. doi: 10.1128/jcm.5.4.393-396.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sondag J. E., Ali M., Murray P. R. Rapid presumptive identification of anaerobes in blood cultures by gas-liquid chromatography. J Clin Microbiol. 1980 Mar;11(3):274–277. doi: 10.1128/jcm.11.3.274-277.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Todd J. K., Roe M. H. Rapid detection of bacteremia by an early subculture technic. Am J Clin Pathol. 1975 Nov;64(5):694–699. doi: 10.1093/ajcp/64.5.694. [DOI] [PubMed] [Google Scholar]
