Abstract
A retrospective study was done to determine the epidemiology of infection and/or colonization due to Pseudomonas aeruginosa in a Brazilian general hospital. In 1966, 1968, and 1969, there were only two instances where probable cross-contamination was shown; the remaining isolates were unrelated. In late 1971 the hospital experienced a marked increase in P. aeruginosa isolation. Contaminated dextrose solutions used in the infant feeding were the apparent cause of the problem which occurred in the premature and special care nurseries. A contaminated oxygen humidifying bottle was the source of a different outbreak in surgery. There was also evidence in four instances that cross-infection and/or contamination had occurred. Pyocin and serological typing revealed that many strains were involved and led to a clear understanding of the complex epidemiological relationships among all the strains.
Full text
PDF





Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bassett D. C., Thompson S. A., Page B. Neonatal infections with Pseudomonas aeruginosa associated with contaminated resuscitation equipment. Lancet. 1965 Apr 10;1(7389):781–784. doi: 10.1016/s0140-6736(65)92955-7. [DOI] [PubMed] [Google Scholar]
- Bobo R. A., Newton E. J., Jones L. F., Farmer L. H., Farmer J. J., 3rd Nursery outbreak of Pseudomonas aeruginosa: epidemiological conclusions from five different typing methods. Appl Microbiol. 1973 Mar;25(3):414–420. doi: 10.1128/am.25.3.414-420.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cartwright R. Y., Hargrave P. R. Pseudomonas in ventilators. Lancet. 1970 Jan 3;1(7636):40–40. doi: 10.1016/s0140-6736(70)90553-2. [DOI] [PubMed] [Google Scholar]
- Chadwick P. the significance of pattern variations in pyocine typing of Pseudomonas aeruginosa. Can J Microbiol. 1972 Jul;18(7):1153–1158. doi: 10.1139/m72-177. [DOI] [PubMed] [Google Scholar]
- Cole A. P., Thom A. R., Watrasiewicz K. Infant carriers of Pseudomonas aeruginosa. Lancet. 1971 Nov 20;2(7734):1155–1155. doi: 10.1016/s0140-6736(71)91314-6. [DOI] [PubMed] [Google Scholar]
- Cooke E. M., Shooter R. A., O'Farrell S. M., Martin D. R. Faecal carriage of Pseudomonas aeruginosa by newborn babies. Lancet. 1970 Nov 21;2(7682):1045–1046. doi: 10.1016/s0140-6736(70)90282-5. [DOI] [PubMed] [Google Scholar]
- DARRELL J. H., WAHBA A. H. PYOCINE-TYPING OF HOSPITAL STRAINS OF PSEUDOMONAS PYOCYANEA. J Clin Pathol. 1964 May;17:236–242. doi: 10.1136/jcp.17.3.236. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Farmer J. J., 3rd, Herman L. G. Epidemiological fingerprinting of Pseudomonas aeruginosa by the production of and sensitivity of pyocin and bacteriophage. Appl Microbiol. 1969 Nov;18(5):760–765. doi: 10.1128/am.18.5.760-765.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Farmer J. J., 3rd Mnemonic for reporting bacteriocin and bacteriophage types. Lancet. 1970 Jul 11;1(7663):96–96. doi: 10.1016/s0140-6736(70)92663-2. [DOI] [PubMed] [Google Scholar]
- Feingold D. S. Hospital-acquired infections. N Engl J Med. 1970 Dec 17;283(25):1384–1391. doi: 10.1056/NEJM197012172832507. [DOI] [PubMed] [Google Scholar]
- Fierer J., Taylor P. M., Gezon H. M. Pseudomonas aeruginosa epidemic traced to delivery-room resuscitators. N Engl J Med. 1967 May 4;276(18):991–996. doi: 10.1056/NEJM196705042761801. [DOI] [PubMed] [Google Scholar]
- Finland M. Excursions into epidemiology: selected studies during the past four decades at Boston City Hospital. J Infect Dis. 1973 Jul;128(1):76–124. doi: 10.1093/infdis/128.1.76. [DOI] [PubMed] [Google Scholar]
- Govan J. R., Gillies R. R. Further studies in the pyocine typing of Pseudomonas pyocyanea. J Med Microbiol. 1969 Feb;2(1):17–25. doi: 10.1099/00222615-2-1-17. [DOI] [PubMed] [Google Scholar]
- HABS I. Untersuchungen über die O-Antigene von Pseudomonas aeruginosa. Z Hyg Infektionskr. 1957;144(3):218–228. [PubMed] [Google Scholar]
- Homma J. Y., Shionoya H., Yamada H., Kawabe Y. Production of antibody against Pseudomonas aeruginosa and its serological typing. Jpn J Exp Med. 1971 Feb;41(1):89–94. [PubMed] [Google Scholar]
- Jones L. F., Pinto B. V., Thomas E. T., Farmer J. J., 3rd Simplified method for producing pyocins from Pseudomonas aeruginosa. Appl Microbiol. 1973 Jul;26(1):120–121. doi: 10.1128/am.26.1.120-121.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jones L. F., Zakanycz J. P., Thomas E. T., Farmer J. J., 3rd Pyocin typing of Pseudomonas aeruginosa: a simplified method. Appl Microbiol. 1974 Feb;27(2):400–406. doi: 10.1128/am.27.2.400-406.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kass E. H. Infectious diseases and social change. J Infect Dis. 1971 Jan;123(1):110–114. doi: 10.1093/infdis/123.1.110. [DOI] [PubMed] [Google Scholar]
- Lowbury E. J., Thom B. T., Lilly H. A., Babb J. R., Whittall K. Sources of infection with Pseudomonas aeruginosa in patients with tracheostomy. J Med Microbiol. 1970 Feb;3(1):39–56. doi: 10.1099/00222615-3-1-39. [DOI] [PubMed] [Google Scholar]
- Moody M. R., Young V. M., Kenton D. M., Vermeulen G. D. Pseudomonas aeruginosa in a center for cancer research. I. Distribution of intraspecies types from human and environmental sources. J Infect Dis. 1972 Feb;125(2):95–101. doi: 10.1093/infdis/125.2.95. [DOI] [PubMed] [Google Scholar]
- Mushin R., Ziv G. Epidemiological aspects of Pseudomonas aeruginosa in man, animals and the environment. Application of pyocin typing. Isr J Med Sci. 1973 Feb;9(2):155–161. [PubMed] [Google Scholar]
- Myerowitz R. L., Medeiros A. A., O'Brien T. F. Recent experience with bacillemia due to gram-negative organisms. J Infect Dis. 1971 Sep;124(3):239–246. doi: 10.1093/infdis/124.3.239. [DOI] [PubMed] [Google Scholar]
- Pennington J. E., Reynolds H. Y., Carbone P. P. Pseudomonas pneumonia. A retrospective study of 36 cases. Am J Med. 1973 Aug;55(2):155–160. doi: 10.1016/0002-9343(73)90163-0. [DOI] [PubMed] [Google Scholar]
- Rees T. A. Bacteria in suction machines. Lancet. 1970 Jan 31;1(7640):240–240. doi: 10.1016/s0140-6736(70)90594-5. [DOI] [PubMed] [Google Scholar]
- Saroff A. L., Armstrong D., Johnson W. D. Pseudomonas endocarditis. Am J Cardiol. 1973 Aug;32(2):234–237. doi: 10.1016/s0002-9149(73)80127-4. [DOI] [PubMed] [Google Scholar]
- Shooter R. A., Gaya H., Cooke E. M., Kumar P., Patel N., Parker M. T., Thom B. T., France D. R. Food and medicaments as possible sources of hospital strains of Pseudomonas aeruginosa. Lancet. 1969 Jun 21;1(7608):1227–1229. doi: 10.1016/s0140-6736(69)92114-x. [DOI] [PubMed] [Google Scholar]
- TEPLITZ C., DAVIS D., MASON A. D., Jr, MONCRIEF J. A. PSEUDOMONAS BURN WOUND SEPSIS. I PATHOGENESIS OF EXPERIMENTAL PSEUDOMONAS BURN WOUND SEPSIS. J Surg Res. 1964 May;4:200–216. doi: 10.1016/s0022-4804(64)80026-3. [DOI] [PubMed] [Google Scholar]
- TEPLITZ C., DAVIS D., WALKER H. L., RAULSTON G. L., MASON A. D., Jr, MONCRIEF J. A. PSEUDOMONAS BURN WOUND SEPSIS. II HEMATOGENOUS INFECTION AT THE JUNCTION OF THE BURN WOUND AND THE UNBURNED HYPODERMIS. J Surg Res. 1964 May;4:217–222. doi: 10.1016/s0022-4804(64)80027-5. [DOI] [PubMed] [Google Scholar]
- WAHBA A. H. HOSPITAL INFECTION WITH PSEUDOMONAS PYOCYANEA: AN INVESTIGATION BY A COMBINED PYOCINE AND SEROLOGICAL TYPING METHOD. Br Med J. 1965 Jan 9;1(5427):86–89. doi: 10.1136/bmj.1.5427.86. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Whitby J. L., Rampling A. Pseudomonas aeruginosa contamination in domestic and hospital environments. Lancet. 1972 Jan 1;1(7740):15–17. doi: 10.1016/s0140-6736(72)90006-2. [DOI] [PubMed] [Google Scholar]
- Zabransky R. J., Day F. E. Pyocine typing of clinical strains of Pseudomonas aeruginosa. Appl Microbiol. 1969 Feb;17(2):293–296. doi: 10.1128/am.17.2.293-296.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
