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. 1976 Jan;3(1):67–69. doi: 10.1128/jcm.3.1.67-69.1976

Comparison of the complement fixation test and counterelectrophoresis test for the detection of antibodies in Chagas disease.

R A Knight, H Rocha, D Kaye
PMCID: PMC274228  PMID: 815268

Abstract

Sera from 452 patients and blood donors were tested for antibodies to Tryp-anosoma cruzi. The complement fixation test and a counterelectrophoresis test were used. The results showed that both tests agreed in 92% of the sera. However, the counterelectrophoresis test was not as sensitive as the complement fixation test.

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Selected References

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  1. CHAFFEE E. F., FIFE E. H., Jr, KENT J. F. Diagnosis of Trypanosoma cruzi infection by complement fixation. Am J Trop Med Hyg. 1956 Sep;5(5):763–771. doi: 10.4269/ajtmh.1956.5.763. [DOI] [PubMed] [Google Scholar]
  2. DIAS E., LARANJA F. S., MIRANDA A., NOBREGA G. Chagas' disease; a clinical, epidemiologic, and pathologic study. Circulation. 1956 Dec;14(6):1035–1060. doi: 10.1161/01.cir.14.6.1035. [DOI] [PubMed] [Google Scholar]
  3. FIFE E. H., Jr, MUSCHEL L. H. Fluorescent-antibody technic for serodiagnosis of Trypanosoma cruzi infection. Proc Soc Exp Biol Med. 1959 Jul;101(3):540–543. doi: 10.3181/00379727-101-25009. [DOI] [PubMed] [Google Scholar]
  4. KNIERIM F. Resultados obtenidos con la reacción de fijación del complemento según el 50% de hemólisis en el diagnóstico de la enfermedad de Chagas. Bol Chil Parasitol. 1959 Jan-Mar;14(1):5–6. [PubMed] [Google Scholar]
  5. Montaño G., Ucrós H. Comparación entre las reacciones de hemaglutinación y fijación del complemento en el diagnóstico serológico de la enfermedad de Chagas. Bol Chil Parasitol. 1965 Jul-Sep;20(3):62–67. [PubMed] [Google Scholar]

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