Abstract
A computer program was developed to identify bacteria solely on the basis of their relative susceptibility to various antimicrobial agents. A sample of 481 clinical isolates from nine of the most commonly isolated gram-negative groups was identified by the quadratic discriminant function technique. Various combinations of antimicrobials were tried, and one set of 18 resulted in a more than 97% correlation with conventional identification procedures. The antimicrobial set could be decreased to 14, while a better than 95% correlation with the conventional procedures was maintained.
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Selected References
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- Friedman R., MacLowry J. Computer identification of bacteria on the basis of their antibiotic susceptibility patterns. Appl Microbiol. 1973 Sep;26(3):314–317. doi: 10.1128/am.26.3.314-317.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gilardi G. L. Antimicrobial susceptibility as a diagnostic aid in the identification of nonfermenting gram-negative bacteria. Appl Microbiol. 1971 Nov;22(5):821–823. doi: 10.1128/am.22.5.821-823.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Grams R. R., Johnson E. A., Benson E. S. Laboratory data analysis system. 3. Multivariate normality. Am J Clin Pathol. 1972 Aug;58(2):188–200. doi: 10.1093/ajcp/58.2.188. [DOI] [PubMed] [Google Scholar]
- Grams R. R., Johnson E. A., Benson E. S. Laboratory data analysis system. IV. Multivariate diagnosis. Am J Clin Pathol. 1972 Aug;58(2):201–207. doi: 10.1093/ajcp/58.2.201. [DOI] [PubMed] [Google Scholar]
- Sutter V. L., Finegold S. M. Antibiotic disc susceptibility tests for rapid presumptive identification of Gram-negative anaerobic bacilli. Appl Microbiol. 1971 Jan;21(1):13–20. doi: 10.1128/am.21.1.13-20.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]