Figure 2. Nestin-immunoreactive (-IR) cells and vessels in the dentate gyrus (DG) from a 29 years old male with Major Depressive Disorder (MDD) who was not on medication (a) and a 31 years old male MDD who was treated with fluoxetine (b).
(a) The subgranular zone (SGZ) and granule cell layer (GCL) are indicated. Cells are stained for Nissl with Cresyl Violet. Nestin-IR cells and vessels appear in brown. (b) The fluoxetine-treated MDD shows more prominent nestin-IR cells processes and vessels compared to the untreated MDD (in a).