Abstract
Results of serotyping 966 clinical isolates of Pseudomonas aeruginosa showed that 72% agglutinated specifically in one or another of the 16 typing antisera, but 28% agglutinated in two or more and often in as many as 10 antisera; this polyagglutinability correlated with a high incidence of cross-reactivity among the antisera. Absorption of each typing antiserum with either cell suspensions of five O-type strains or with a suspension of a particular polyagglutinable strain (SMC 247) abolished cross-reactivity in the typing antisera without significantly reducing titers against the homologous strains. All but four of the polyagglutinable strains agglutinated specifically in one or another absorbed antisera. The cross-reactions of unabsorbed antisera were interpreted to have been caused by antibodies directed not against specific O antigens but against thermostable specificities that remain undefined.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bergan T. Epidemiological markers for Pseudomonas aeruginosa. 1. Serogrouping, pyocine typing--and their interrelations. Acta Pathol Microbiol Scand B Microbiol Immunol. 1973 Feb;81(1):70–80. [PubMed] [Google Scholar]
- Chester I. R., Meadow P. M., Pitt T. L. The relationship between the O-antigenic lipopolysaccharides and serological specificity in strains of Pseudomonas aeruginosa of different O-serotypes. J Gen Microbiol. 1973 Oct;78(2):305–318. doi: 10.1099/00221287-78-2-305. [DOI] [PubMed] [Google Scholar]
- Duncan I. B., Booth E. V. Epidemiology of Pseudomonas aeruginosa infections investigated by pyocin typing. Can Med Assoc J. 1975 Apr 5;112(7):837–843. [PMC free article] [PubMed] [Google Scholar]
- HABS I. Untersuchungen über die O-Antigene von Pseudomonas aeruginosa. Z Hyg Infektionskr. 1957;144(3):218–228. [PubMed] [Google Scholar]
- Homma J. Y., Kim K. S., Yamada H., Ito M., Shionoya H. Serological typing of Pseudomonas aeruginosa and its cross-infection. Jpn J Exp Med. 1970 Oct;40(5):347–359. [PubMed] [Google Scholar]
- Lányi B. Serological properties of Pseudomonas aeruginosa. I. Group-specific somatic antigens. Acta Microbiol Acad Sci Hung. 1966;13(4):295–318. [PubMed] [Google Scholar]
- Mikkelsen O. S. Serotyping of Pseudomonas aerunginosa. I. Studies on the production of anti O sera. Acta Pathol Microbiol Scand. 1968;73(3):373–390. [PubMed] [Google Scholar]
- SANDVIK O. Serological comparison between strains of Pseudomonas aeruginosa from human and animal sources. Acta Pathol Microbiol Scand. 1960;48:56–60. doi: 10.1111/j.1699-0463.1960.tb04738.x. [DOI] [PubMed] [Google Scholar]
- VERDER E., EVANS J. A proposed antigenic schema for the identification of strains of Pseudomonas aeruginosa. J Infect Dis. 1961 Sep-Oct;109:183–193. doi: 10.1093/infdis/109.2.183. [DOI] [PubMed] [Google Scholar]
- WAHBA A. H. HOSPITAL INFECTION WITH PSEUDOMONAS PYOCYANEA: AN INVESTIGATION BY A COMBINED PYOCINE AND SEROLOGICAL TYPING METHOD. Br Med J. 1965 Jan 9;1(5427):86–89. doi: 10.1136/bmj.1.5427.86. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wilkinson S. G., Galbrath L. Studies of lipopolysaccharides from Pseudomonas aeruginosa. Eur J Biochem. 1975 Mar 17;52(2):331–343. doi: 10.1111/j.1432-1033.1975.tb04001.x. [DOI] [PubMed] [Google Scholar]