Table 2.
TRIAL | SALINE | CLOZAPINE (mg/kg) | PD149163 (mg/kg) | ||||
---|---|---|---|---|---|---|---|
0.1 | 1.0 | 10 | 0.01 | 0.3 | 1.0 | ||
Learning Exposure | 125.71 ± 6.71 | 91.13 ± 18.09 | 88.33 ± 14.10 | 85.50 ± 15.97* | 72.36 ± 22.26** | 53.27 ± 12.42** | 69.60 ± 14.96** |
Test Period- Novel Juvenile |
55.10 ± 3.90 | 43.50 ± 10.91 | 41.67 ± 8.48 | 50.63 ± 14.32 | 62.64 ± 10.57 | 55.27 ± 13.89 | 66.87 ± 14.85 |
Test Period- Familiar Juvenile |
47.38 ± 3.46 | 44.88 ± 8.87 | 20.67 ± 4.41** | 21.13 ± 5.34** | 47.09 ± 7.35 | 24.09 ± 7.94** | 31.13 ± 8.11* |
Mean ± Std.
Error Mean P< 0.05 significantly less time spent investigating versus the saline-treated rats.
Error Mean P<0.01 significantly less time spent investigating versus the saline-treated rats.