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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Neuropsychopharmacology. 2009 Mar 25;34(8):2011–2018. doi: 10.1038/npp.2009.15

Table 2.

Social Interaction Time (seconds) Exhibited by Brattleboro Rats

TRIAL SALINE CLOZAPINE (mg/kg) PD149163 (mg/kg)
0.1 1.0 10 0.01 0.3 1.0
Learning Exposure 125.71 ± 6.71 91.13 ± 18.09 88.33 ± 14.10 85.50 ± 15.97* 72.36 ± 22.26** 53.27 ± 12.42** 69.60 ± 14.96**
Test Period-
Novel Juvenile
55.10 ± 3.90 43.50 ± 10.91 41.67 ± 8.48 50.63 ± 14.32 62.64 ± 10.57 55.27 ± 13.89 66.87 ± 14.85
Test Period-
Familiar Juvenile
47.38 ± 3.46 44.88 ± 8.87 20.67 ± 4.41** 21.13 ± 5.34** 47.09 ± 7.35 24.09 ± 7.94** 31.13 ± 8.11*

Mean ± Std.

*

Error Mean P< 0.05 significantly less time spent investigating versus the saline-treated rats.

**

Error Mean P<0.01 significantly less time spent investigating versus the saline-treated rats.