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. 1976 Sep;4(3):288–295. doi: 10.1128/jcm.4.3.288-295.1976

Interference by Neisseria gonorrhoeae growth by other bacterial species.

S J Kraus, R C Geller, G H Perkins, D L Rhoden
PMCID: PMC274452  PMID: 823175

Abstract

Growth of Neisseria gonorrhoeae from clinical specimens has been enhanced by the use of selective media that inhibit the simultaneous growth of other microorganisms. One explanation for this enhancement could be that certain other bacteria inhibit gonococcal growth. This hypothesis was examined by testing 167 bacterial isolates for in vitro gonococcal inhibition; 34.1% of the isolates failed to inhibit the gonococcus, but 12.0% produced weak inhibition and 53.9% strongly inhibited N. gonorrhoeae. The pattern of in vitro gonococcal inhibition was consistently the same for all the individual isolates within some species, but individual isolates within other bacterial species varied in their ability to inhibit the gonococcus. Consistently strong in vitro N. gonorrhoeae inhibitors were Citrobacter diversus, Enterobacter cloacae, Serratia marcescens, and Pseudomonas. The in vivo significance of gonococcal interference was demonstrated in the subcutaneous chamber model of N. gonorrhoeae infection.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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