Abstract
An orgainsm was isolated from a kidney biopsy of a patient with renal failure. Electron microscopy revealed an ultrastructure very similar to that of a bacterial L-form or mycoplasma. But macroscopically, its colonial morphology was unusual and distinct from that ascribed to these wall-less organisms. This isolate lacked a rigid cell wall and required a hypertonic medium with serum for growth. Also, a long incubation period was essential for its growth, and use of hand lens was necessary for detection on solid medium.
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- Domingue G., Turner B., Schlegel J. U. Cell-wall deficient bacterial variants in kidney tissue. Detection by immunofluorescence. Urology. 1974 Mar;3(3):288–292. doi: 10.1016/s0090-4295(74)80105-6. [DOI] [PubMed] [Google Scholar]
- Fernandes P. B., Panos C. Persistence, pathogenesis, and morphology of an L-form of Streptococcus pyogenes adapted to physiological isotonic conditions when in immunosuppressed mice. Infect Immun. 1976 Nov;14(5):1228–1240. doi: 10.1128/iai.14.5.1228-1240.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Leon O., Panos C. Adaptation of an osmotically fragile L-form of Streptococcus pyogenes to physiological osmotic conditions and its ability to destroy human heart cells in tissue culture. Infect Immun. 1976 Jan;13(1):252–262. doi: 10.1128/iai.13.1.252-262.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]