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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1977 Jun;5(6):625–628. doi: 10.1128/jcm.5.6.625-628.1977

Electron capture gas chromatography detection and mass spectrum identification of 3-(2'-ketohexyl)indoline in spinal fluids of patients with tuberculous meningitis.

J B Brooks, G Choudhary, R B Craven, C C Alley, J A Liddle, D C Edman, J D Converse
PMCID: PMC274668  PMID: 886002

Abstract

A basic, extractable, indolic type of compound, which was derivatized with heptafluorobutyric anhydride and pyridine, was obtained from the cerebrospinal fluids of patients with acute tuberculous meningitis. The compound was detected by frequency-pulsed, modulated electron capture gas-liquid chromatography, and it was tentatively identified by mass spectrometry as 3-(2'-ketohexyl)indoline. The compound was found to be valuable for differentiating between tuberculous, cryptococcal, and aseptic meningitides.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Koslow S. H., Green A. R. Analysis of pineal and brain indole alkylamines by gas chromatography-mass spectrometry. Adv Biochem Psychopharmacol. 1973;7:33–43. [PubMed] [Google Scholar]

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