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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1975 Feb;1(2):201–205. doi: 10.1128/jcm.1.2.201-205.1975

Large-scale production of rubella precipitinogens and their use in the diagnostic laboratory.

R Cappel, A Schluederberg, D M Horstmann
PMCID: PMC275019  PMID: 809471

Abstract

A method for producing large quantities of rubella theta and iota precipitating antigens in Vero cells is described. Using this reagent, the detection of anti-theta antibodies was found to be as sensitive as the hemagglutination inhibition test for both the determination of immune status and the diagnosis of acute rubella infection. The detection of anti-iota antibodies may permit diagnosis of rubella infection, when the collection of the first serum has been delayed and the early rise of hemagglutin-inhibiting and anti-theta antibodies has been missed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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