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. 2004 Jun 8;5(3):38–42. doi: 10.1208/pt050341

Effect of molecular weight of hydrolyzed gelatin on its binding properties in tablets: A technical note

Suruchi N Kokil 1, Pradeep R Patil 1, Kakasaheb R Mahadik 2, Anant R Paradkar 1,✉
PMCID: PMC2750264  PMID: 15760074

Conclusion

Hydrolyzed gelatins (Byco-A, Byco-O and Byco-C), when used as binders, yielded soft, uniform granules with good flow properties. As the molecular weight and viscosity of hydrolyzed gelatins increased, the compressibility of granules decreased and their compactability increased. The balance between compressibility and compactability of granules may be achieved by careful monitoring of the molecular weight of hydrolyzed gelatins that can serve as potential binders.

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