Abstract
A method for detecting toxin production in Corynebacterium diphtheriae cultures by counterimmunoelectrophoresis is described. Precipitin lines were observed in toxigenic strains in 30 min.
Full text
PDF

Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bickham S. T., Jones W. L. Problems in the use of the in vitro toxigenicity test for Corynebacterium diphtheriae. Am J Clin Pathol. 1972 Feb;57(2):244–246. doi: 10.1093/ajcp/57.2.244. [DOI] [PubMed] [Google Scholar]
- ELEK S. D. The plate virulence test for diphtheria. J Clin Pathol. 1949 Nov;2(4):250–258. doi: 10.1136/jcp.2.4.250. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Edwards E. A. Immunologic investigations of meningococcal disease. I. Group-specific Neisseria meningitidis antigens present in the serum of patients with fulminant meningococcemia. J Immunol. 1971 Feb;106(2):314–317. [PubMed] [Google Scholar]
- FROBISHER M., Jr, KING E. O., PARSONS E. I. A test in vitro for virulence of Corynebacterium diphtheriae. Am J Clin Pathol. 1951 Mar;21(3):282–285. [PubMed] [Google Scholar]
- Fossieck B., Jr, Craig R., Paterson P. Y. Counterimmunoelectrophoresis for rapid diagnosis of meningitis due to Diplococcus pneumoniae. J Infect Dis. 1973 Jan;127(1):106–109. doi: 10.1093/infdis/127.1.106. [DOI] [PubMed] [Google Scholar]
- Gocke D. J., Howe C. Rapid detection of Australia antigen by counterimmunoelectrophoresis. J Immunol. 1970 Apr;104(4):1031–1034. [PubMed] [Google Scholar]
- HERMANN G. J., MOORE M. S., PARSONS E. I. A substitute for serum in the diphtheria in vitro toxigenicity test. Am J Clin Pathol. 1958 Feb;29(2):181–183. doi: 10.1093/ajcp/29.2_ts.181. [DOI] [PubMed] [Google Scholar]
- Hill H. R., Riter M. E., Menge S. K., Johnson D. R., Matsen J. M. Rapid identification of group B streptococci by counterimmunoelectrophoresis. J Clin Microbiol. 1975 Feb;1(2):188–191. doi: 10.1128/jcm.1.2.188-191.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ingram D. L., Anderson P., Smith D. H. Countercurrent immunoelectrophoresis in the diagnosis of systemic diseases caused by Hemophilus infleunzae type b. J Pediatr. 1972 Dec;81(6):1156–1159. doi: 10.1016/s0022-3476(72)80252-x. [DOI] [PubMed] [Google Scholar]
- KING E. O., FROBISHER M., Jr, PARSONS E. I. The in vitro test for virulence of Corynebacterium diphtheriae. Am J Public Health Nations Health. 1949 Oct;39(10):1314–1320. doi: 10.2105/ajph.39.10.1314. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Laird W., Groman N. Rapid, direct tissue culture test for toxigenicity of Corynebacterium diphtheriae. Appl Microbiol. 1973 May;25(5):709–712. doi: 10.1128/am.25.5.709-712.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Nagel J. G., Tuazon C. U., Cardella T. A., Sheagren J. N. Teichoic acid serologic diagnosis of staphylococcal endocarditis. Use of gel diffusion and counterimmunoelectrophoretic methods. Ann Intern Med. 1975 Jan;82(1):13–17. doi: 10.7326/0003-4819-82-1-13. [DOI] [PubMed] [Google Scholar]
- Schubert J. H., Bickham S. T., Wiggins G. L. Tissue culture method for toxigenicity testing of Corynebacterium diphtheriae. Appl Microbiol. 1968 Nov;16(11):1748–1752. doi: 10.1128/am.16.11.1748-1752.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Young P. S., Smith D. D. The detection of toxin production by Corynebacterium diphtheriae in diagnostic laboratories. Pathology. 1976 Apr;8(2):101–104. doi: 10.3109/00313027609094434. [DOI] [PubMed] [Google Scholar]

