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. Author manuscript; available in PMC: 2009 Sep 24.
Published in final edited form as: Nature. 2009 Feb 12;457(7231):877–881. doi: 10.1038/nature07744

Fig. 3. Convergent gene duplication expansion in African great apes but not humans.

Fig. 3

a) Two regions on chromosome 10 have expanded in chimpanzee, gorilla and bonobo when compared to human based on computational and interspecific arrayCGH experiments (see Fig. 1 legend). b) FISH confirms 23-50 copies in chimpanzee and bonobo, and >100 copies in gorilla (Methods). End-sequence pair analysis using gorilla and chimpanzee WGS sequences reveals that all but the ancestral location are nonorthologous, indicating independent expansions in both lineages. c) Detailed analysis of 8 homologues of gorilla chromosome 1 reveal interstitial locations of the block 2 duplication that show variation both in copy number and in terms of location.