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. 1978 Aug;8(2):233–237. doi: 10.1128/jcm.8.2.233-237.1978

Detection of antibody to bovine syncytial virus and respiratory syncytial virus in bovine fetal serum.

E A Gould, G M Allan, E F Logan, J B McFerran
PMCID: PMC275192  PMID: 100508

Abstract

Batches of commercial fetal bovine serum, described by the suppliers as antibody-free, all contained antibody to bovine syncytial virus (BSV) when tested by indirect immunofluorescence. Antibody to bovine respiratory syncytial virus (RSV) was not detected in these sera. Twenty-four percent of individual fetal bovine sera contained antibody to BSV, and 14% contained antibody to RSV when tested by indirect immunofluorescence. BSV antibody titers in fetal sera from dams with high BSV antibody levels were variable but always higher than RSV antibody titers. Radial immunodiffusion studies with BSV-positive sera revealed the presence of immunoglobulin M (IgM), IgG, and IgA, but the quantity of these immunoglobulins was not directly related to the BSV antibody titers. The evidence suggests that the antibody present in fetal sera arose as the result of infection rather than from maternal transfer across the placenta.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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