Table 4.
One-variable models | Two-variable model | |||||||
---|---|---|---|---|---|---|---|---|
Adjusted Cross-sectional volume | APC | Adjusted Cross-sectional volume | APC | |||||
HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
Hippocampus | 1.51 (1.1, 2.0) | 0.002 | 1.13 (0.8, 1.5) | 0.23 | 1.51 (1.1, 2.0) | 0.003 | 1.06 (0.8, 1.5) | 0.37 |
ERC | 1.22 (0.9, 1.7) | 0.12 | 1.13 (0.8, 1.5) | 0.23 | 1.21 (0.9, 1.7) | 0.14 | 1.10 (0.8, 1.5) | 0.28 |
Whole brain | 1.33 (0.9, 1.9) | 0.05 | 1.37 (1.1, 1.8) | 0.007 | 1.17 (0.8, 1.7) | 0.21 | 1.30 (1.0, 1.7) | 0.034 |
Ventricle | 1.03 (0.8, 1.4) | 0.43 | 1.71 (1.3, 2.3) | <0.001 | 0.97 (0.7, 1.3) | 0.58 | 1.72 (1.3, 2.4) | <0.001 |
Note: There were 39 observed conversion among the MCI cohort.
Follow-up starts with second scan.
HR = Hazard Ratio for a 1-standard deviation decrease in cross-sectional volume or annual percent change in volume (except for ventricle estimate which is based on a 1-standard deviation increases).