Figure 4. Adipokine levels in Rag-1 KO and Rag-1 APN KO after transfer of RB^high cells.

Expression of APN and leptin in mesenteric adipose tissue of WT (light gray bars), APN KO (dark gray bars), Rag-1 KO (white bars) and Rag-1 APN KO mice (black bars) was determined by real-time RT-PCR (A and D). Data are expressed as fold induction compared with control WT mice that did not receive RB^high cells. Adiponectin and leptin levels were measured in serum (B and D) and in colon culture supernatants (C) in WT (light gray bars), APN KO (dark gray bars), Rag-1 KO (white bars) and Rag-1 APN KO mice (black bars) by ELISA. Data are mean +/− SEM, n=5-13 mice per group. *p<0.05, ***p<0.001