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Glossary
- A1AT
alpha-1 antitrypsin
- AL
primary amyloidosis
- APB
abnormal protein bands
- ASCT
autologous stem cell transplantation
- BJP
Bence Jones protein
- BM
bone marrow
- BNP
brain natriuretic peptide (also as NT-proBNP)
- CE
capillary electrophoresis
- CL
constant domain of the light chains; also as Cκ and Cλ
- CR
complete response
- CRAB
Calcium elevation, Renal dysfunction, Anaemia, Bone disease
- Da
Dalton, the atomic mass unit, approximately the mass of a hydrogen atom
- EFS
event-free survival
- ELISA
enzyme-linked immunosorbent assay
- EP
electrophoresis (e.g. zone EP)
- Fab
portion of the antibody that binds antigen
- Fc
portion of the antibody that binds cell surface receptors and some complement proteins
- FLC
free light chains
- IEF
isoelectric focusing
- IFE
immunofixation electrophoresis
- IIMM
intact immunoglobulin myeloma
- INA
immunonephelometric assay
- ITA
immunoturbidimetric assay
- LCDD
light chain deposition disease
- LoD
limit of detection
- M
monoclonal (e.g. M-protein, also called paraprotein)
- MB
monoclonal band
- MGUS
M-gammopathy of undetermined significance
- MM
multiple myeloma
- MW
molecular weight
- NFkB
nuclear factor kappa-light-chain-enhancer of activated B cells
- NSMM
non-secretory multiple myeloma
- OB
oligoclonal band
- OS
overall survival
- PCD
plasma cell disorder/dyscrasia
- PCPD
plasma cell proliferative disorder
- PD
progressive disease
- pI
the isoelectric pH; the pH at which the species carries no net charge
- pK
-logKa, the acid dissociation constant; a pH of maximum buffering
- POEMS
polyneuropathy, organomegaly, endocrinopathy, M-gammopathy and skin changes
- PR
partial response
- PVDF
polyvinylidene fluoride
- sCR
stringent CR
- SMM
smouldering multiple myeloma
- SPEP
serum protein electrophoresis
- UPEP
urine protein electrophoresis
- vgPR
very good partial response
- VL
variable domain of the light chains; also as Vκ and Vλ
- WM
Waldenström’s macroglobulinaemia