Table 6.

Area under the Receiving Operator Characteristic Curve (AROC) Sensitivity and Specificity Analyses for Combined Retinal Nerve Fiber Layer (RNFL) Parameters

RNFL Thickness Parameters	AROC (SE)	Sensitivity < 5%*	Specificity < 5%*	Sensitivity < 1%†	Specificity < 1%†
Overall	0.890 (0.025)	0.406 (0.05)	1.0 (0)	0.180 (0.041)	1.0 (0)
Inferior or superior quadrant	0.921 (0.02)	0.654 (0.046)	0.966 (0.016)	0.421 (0.046)	0.994 (0.006)
Any quadrant	0.893 (0.023)	0.662 (0.046)	0.937 (0.02)	0.421 (0.046)	0.994 (0.006)
Overall, inferior, or superior quadrant	0.922 (0.021)	0.654 (0.046)	0.966 (0.016)	0.421 (0.046)	0.994 (0.006)
Overall or any quadrant	0.894 (0.023)	0.662 (0.046)	0.937 (0.02)	0.421 (0.046)	0.994 (0.006)
Select clock hours	0.90 (0.023)	0.782 (0.04)	0.839 (0.032)	0.579 (0.047)	0.971 (0.015)
Any clock hour	0.892 (0.024)	0.797 (0.04)	0.799 (0.035)	0.579 (0.047)	0.966 (0.016)
Overall or select clock hours‡	0.90 (0.023)	0.782 (0.04)	0.839 (0.032)	0.579 (0.047)	0.971 (0.015)
Overall or any clock hour	0.892 (0.024)	0.797 (0.04)	0.799 (0.035)	0.579 (0.047)	0.966 (0.016)
Overall or any quadrants or any clock hour	0.893 (0.024)	0.797 (0.04)	0.793 (0.036)	0.586 (0.046)	0.966 (0.016)
LDF of quadrants	0.922 (0.02)	0.737 (0.043)	0.943 (0.022)	0.541 (0.048)	0.989 (0.008)
LDF of clock hours	0.932 (0.019)	0.820 (0.038)	0.897 (0.029)	0.699 (0.045)	0.977 (0.011)

LDF = linear discriminant function; SE = standard error.

^*Based on fifth percentile cutoff criteria.

^†Based on first percentile cutoff criteria.

^‡Clock hours: 6 right eye (R)/left eye (L), 7 R/5 L, 11 R/1 L, 12 R/L, 5 R/7 L, 1 R/11 L.