Abstract
Feingold, David S. (The University of Pennsylvania School of Medicine, Philadelphia), and Robert Austrian. Transformation of pneumococcal M protein. J. Bacteriol. 92:952–955. 1966.—Antisera prepared with vaccines of noncapsulated pneumococci of a given M protein type and absorbed with organisms of heterologous M protein type agglutinated specifically the homologous organisms. Specific anti-M protein sera can be used as selective reagents to permit isolation of organisms of heterologous M protein type from mixed populations. This capacity of anti-M protein sera was employed to facilitate recovery of intraspecific M protein transformants of pneumococcus. Attempted interspecific transfer of group A β-hemolytic streptococcal M protein to pneumococcus by means of transformation reactions, however, was not accomplished.
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Selected References
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