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. 1966 Oct;92(4):1002–1004. doi: 10.1128/jb.92.4.1002-1004.1966

Cumulative Hemagglutination by Mycoplasma pneumoniae and Other Agglutinins

T Jacob John a,1, Marlene Stahl a, Vincent A Fulginiti a
PMCID: PMC276368  PMID: 4288795

Abstract

John, T. Jacob (University of Colorado School of Medicine, Denver), Marlene Stahl, and Vincent A. Fulginiti. Cumulative hemagglutination by Mycoplasma pneumoniae and other agglutinins. J. Bacteriol. 92:1002–1004. 1966.—The phenomenon of cumulative hemagglutination, or hemagglutination by two agglutinins, each in subagglutinating concentration, was demonstrated by use of four different systems, namely, horse serum and Mycoplasma pneumoniae, horse serum and measles antigen, M. pneumoniae and measles antigen, and parainfluenza 2 virus and M. pneumoniae. Cumulative hemagglutination appears to be the mechanism by which a horse-serum diluent causes high hemagglutination titers of M. pneumoniae, since both contain hemagglutinins against vervet erythrocytes. It was also shown that antibodies against either one of the two antigens may cause inhibition of such hemagglutination.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Feldman H. A., Suhs R. H. Serologic epidemiologic studies with M. pneumoniae. I. Demonstration of an hemagglutinin and its inhibition by antibody. Am J Epidemiol. 1966 Mar;83(2):345–356. doi: 10.1093/oxfordjournals.aje.a120590. [DOI] [PubMed] [Google Scholar]
  2. GRAYSTON J. T., ALEXANDER E. R., KENNY G. E., CLARKE E. R., FREMONT J. C., MACCOLL W. A. MYCOPLASMA PNEUMONIAE INFECTIONS. CLINICAL AND EPIDEMIOLOGIC STUDIES. JAMA. 1965 Feb 1;191:369–374. doi: 10.1001/jama.1965.03080050015004. [DOI] [PubMed] [Google Scholar]
  3. NORRBY E. Hemagglutination by measles virus. 4. A simple procedure for production of high potency antigen for hemagglutination-inhibition (HI) tests. Proc Soc Exp Biol Med. 1962 Dec;111:814–818. doi: 10.3181/00379727-111-27930. [DOI] [PubMed] [Google Scholar]

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