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. 1966 Nov;92(5):1457–1463. doi: 10.1128/jb.92.5.1457-1463.1966

Genetic Analysis of the ViA-his Chromosomal Region in Salmonella

E M Johnson 1, Barbara Krauskopf 1, L S Baron 1
PMCID: PMC276445  PMID: 5332405

Abstract

Johnson, E. M. (Walter Reed Army Institute of Research, Washington, D.C.), Barbara Krauskopf, and L. S. Baron. Genetic analysis of the ViA-his chromosomal region in Salmonella. J. Bacteriol. 92:1457–1463. 1966.—The relative chromosomal location of the ViA determinant, a gene required for Vi antigen expression in Salmonella typhosa (and present also in S. typhimurium), was examined in S. typhimurium × S. typhosa matings. The position of this gene was determined with respect to the histidine (his) and methionine (metG) biosynthesis markers, and to the genetic determinants of somatic antigens 5 (O-5) and 4 (O-4) of S. typhimurium. The gene order established by analyses of the hybrid classes resulting from the genetic crosses was ViA–O-5–metG–O-4 (his). This order suggests that neither ViA nor O-5 is a member of the complex of functionally related structural genes which constitute the O-4 locus. It allows for the possibility, however, of a functional relationship between the genes of the ViA and O-5 loci.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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