Skip to main content
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1967 Feb;93(2):592–596. doi: 10.1128/jb.93.2.592-596.1967

Early Functional Mutants of Coliphage λ

P M Naha a,1
PMCID: PMC276482  PMID: 6020563

Abstract

The early functional mutants of λ, belonging to cistrons N, O, and P, are known to be blocked prior to vegetative multiplication of the λ genome. Superinfection of heteroimmune defective lysogens by these mutants failed to elicit the function required for replication of the superinfecting phage. The mutants among themselves also showed poor cooperation on a nonpermissive host. Studies on the effects of different multiplicities of infection for bacterial lysis showed identical responses for mutants of different cistrons.

Full text

PDF
592

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BROOKS K. STUDIES IN THE PHYSIOLOGICAL GENETICS OF SOME SUPPRESSOR-SENSITIVE MUTANTS OF BACTERIOPHAGE LAMBDA. Virology. 1965 Jul;26:489–499. doi: 10.1016/0042-6822(65)90011-5. [DOI] [PubMed] [Google Scholar]
  2. CAMPBELL A. Sensitive mutants of bacteriophage lambda. Virology. 1961 May;14:22–32. doi: 10.1016/0042-6822(61)90128-3. [DOI] [PubMed] [Google Scholar]
  3. JACOB F., FUERST R., WOLLMAN E. L. Recherches sur les bactéries lysogènes défectives. II. Les types physiologiques liés aux mutations du prophage. Ann Inst Pasteur (Paris) 1957 Dec;93(6):724–753. [PubMed] [Google Scholar]
  4. RADDING C. M. NUCLEASE ACTIVITY IN DEFECTIVE LYSOGENS OF PHAGE MU. II. A HYPERACTIVE MUTANT. Proc Natl Acad Sci U S A. 1964 Oct;52:965–973. doi: 10.1073/pnas.52.4.965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Radding C. M. Nuclease activity in defective lysogens of phage lambda. Biochem Biophys Res Commun. 1964 Feb 18;15(1):8–12. doi: 10.1016/0006-291x(64)90093-2. [DOI] [PubMed] [Google Scholar]
  6. THOMAS R. Effects of chloramphenicol on genetic replication in bacteriophage lambda. Virology. 1959 Oct;9:275–289. doi: 10.1016/0042-6822(59)90120-5. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES