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. 1967 Feb;93(2):749–753. doi: 10.1128/jb.93.2.749-753.1967

Postirradiation Cell Division in 5-Fluorouracil-pretreated Escherichia coli

R Ben-Ishai 1, N Zeevi 1
PMCID: PMC276504  PMID: 5335972

Abstract

The correlation between 5-fluorouracil-induced resistance to ultraviolet (UV) light and the ability of bacterial cells to repair irradiation damage was investigated in various strains of Escherichia coli. Preincubation with 5-fluorouracil did not influence the dark-repair mechanism. It affected, however, the UV light-induced damage of cell division in filament-forming strains. It is suggested that the delay in postirradiation macromolecular synthesis of 5-fluorouracil-pretreated bacteria plays a decisive role in the recovery process leading to cross cell wall-forming ability in the damaged strains.

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Selected References

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