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. 1967 Apr;93(4):1236–1241. doi: 10.1128/jb.93.4.1236-1241.1967

Drug Resistance of Enteric Bacteria VIII. Chromosomal Location of Nontransferable R Factor in Escherichia coli

Kenji Harada 1, Mitsuo Kameda 1, Mitsue Suzuki 1, Susumu Shigehara 1, Susumu Mitsuhashi 1
PMCID: PMC276591  PMID: 5340305

Abstract

The R21(TC) factor, obtained by transduction of the R10(TC.CM.SM.SA) factor with phage ε to group E Salmonella, is not transferable by the normal conjugal process. However, when R21(TC)+ transductants are infected with the F13 factor, the nontransferable R21(TC) factor acquires transmissibility by conjugation. R21(TC)+ conjugants of Escherichia coli K-12, to which only the R21(TC) factor was transmitted by cell-to-cell contact from an F′ R+ donor, were still unable to transfer their R21(TC) factor by conjugation. In crosses between Hfr and F−E. coli K-12 strains containing R21(TC), the gene responsible for tetracycline resistance was located on the E. coli K-12 chromosome between lac and pro, near lac.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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