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. 1967 Oct;94(4):1154–1161. doi: 10.1128/jb.94.4.1154-1161.1967

Effect of Streptomycin Deprivation on Enzyme Synthesis in Streptomycin-Dependent Escherichia coli

R E Goodman a,1, Charles R Spotts a
PMCID: PMC276788  PMID: 4860910

Abstract

During growth of streptomycin-dependent strains of Escherichia coli in the absence of streptomycin (deprived growth), both constitutive and inducible synthesis of β-galactosidase were preferentially inhibited. A similar preferential inhibition of constitutive and derepressed synthesis of alkaline phosphatase was observed. Catabolite repression accounted for part, but not all, of the inhibition of the inducible β-galactosidase synthesis. Serological experiments indicated that that part of the inhibition specificially associated with streptomycin deprivation was not a result of the production of altered β-galactosidase. It is suggested that during deprived growth the ribosomes of streptomycin-dependent bacteria become impaired in their ability to translate certain messages.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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