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Journal of Bacteriology logoLink to Journal of Bacteriology
. 1967 Nov;94(5):1480–1483. doi: 10.1128/jb.94.5.1480-1483.1967

Cryptococcus neoformans II. Phagocytosis by Human Leukocytes

G S Bulmer 1, M D Sans 1
PMCID: PMC276851  PMID: 4862192

Abstract

Twenty-four per cent of the leukocytes from healthy human subjects phagocytized an encapsulated strain of Cryptococcus neoformans. Phagocytosis was approximately three times more effective with nonencapsulated mutants of C. neoformans. When the mutants reverted to the encapsulated state, the percentages of phagocytosis decreased. These data indicate that cryptococcal polysaccharide inhibits the phagocytosis of C. neoformans by human leukocytes.

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Selected References

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