Skip to main content
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1967 Nov;94(5):1582–1593. doi: 10.1128/jb.94.5.1582-1593.1967

Comparative Control of a Branch-Point Enzyme in Microorganisms

Roy A Jensen 1,2, DeLill S Nasser 1,2, Eugene W Nester 1,2
PMCID: PMC276866  PMID: 4964483

Abstract

Thirty-two genera of microorganisms were identified with one of six distinctive control patterns for the enzyme 3-deoxy-d-arabino-heptulosonate-7-phosphate synthetase. These patterns included sequential feedback inhibition, isoenzyme feedback inhibition, cumulative feedback inhibition, and three (apparent) simple one-effector patterns. Documentation is provided of an overwhelming tendency for control patterns to be strongly conserved among the member species of the various genera that were examined.

Full text

PDF
1582

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ackrell B. A., Asato R. N., Mower H. F. Multiple forms of bacterial hydrogenases. J Bacteriol. 1966 Oct;92(4):828–838. doi: 10.1128/jb.92.4.828-838.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BROWN K. D., DOY C. H. END-PRODUCT REGULATION OF THE GENERAL AROMATIC-PATHWAY IN ESCHERICHIA COLI W. Biochim Biophys Acta. 1963 Sep 3;77:170–172. doi: 10.1016/0006-3002(63)90489-x. [DOI] [PubMed] [Google Scholar]
  3. CHAPMAN L. F., CIRILLO V. P., JAHN T. L. PERMEABILITY TO SUGARS AND FATTY ACIDS IN POLYTOMA OBTUSUM. J Protozool. 1965 Feb;12:47–51. doi: 10.1111/j.1550-7408.1965.tb01810.x. [DOI] [PubMed] [Google Scholar]
  4. Courtright J. B., Imberski R. B., Ursprung H. The genetic control of alcohol dehydrogenase and octanol dehydrogenase isozymes in Drosophila. Genetics. 1966 Nov;54(5):1251–1260. doi: 10.1093/genetics/54.5.1251. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. DATTA P., GEST H. CONTROL OF ENZYME ACTIVITY BY CONCERTED FEEDBACK INHIBITION. Proc Natl Acad Sci U S A. 1964 Oct;52:1004–1009. doi: 10.1073/pnas.52.4.1004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Focht D. D., Lockhart W. R. Numerical survey of some bacterial taxa. J Bacteriol. 1965 Nov;90(5):1314–1319. doi: 10.1128/jb.90.5.1314-1319.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Goldberg I. D., Gwinn D. D., Thorne C. B. Interspecies transformation between Bacillus subtilis and Bacillus licheniformis. Biochem Biophys Res Commun. 1966 May 25;23(4):543–548. [PubMed] [Google Scholar]
  8. HANSEN A. J., WEEKS O. B., COLWELL R. R. TAXONOMY OF PSEUDOMONAS PISCICIDA (BEIN) BUCK, MEYERS, AND LEIFSON. J Bacteriol. 1965 Mar;89:752–761. doi: 10.1128/jb.89.3.752-761.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Hoch J. A., DeMoss R. D. Physiological role of tryptophanase in control of tryptophan biosynthesis in Bacillus alvei. J Bacteriol. 1966 Feb;91(2):667–672. doi: 10.1128/jb.91.2.667-672.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hoch J. A., Demoss R. D. Physiological Effects of a Constitutive Tryptophanase in Bacillus alvei. J Bacteriol. 1965 Sep;90(3):604–610. doi: 10.1128/jb.90.3.604-610.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. JENSEN R. A., NESTER E. W. THE REGULATORY SIGNIFICANCE OF INTERMEDIARY METABOLITES: CONTROL OF AROMATIC ACID BIOSYNTHESIS BY FEEDBACK INHIBITION IN BACILLUS SUBTILIS. J Mol Biol. 1965 Jun;12:468–481. doi: 10.1016/s0022-2836(65)80270-4. [DOI] [PubMed] [Google Scholar]
  12. Jensen R. A., Nester E. W. Regulatory enzymes of aromatic amino acid biosynthesis in Bacillus subtilis. I. Purification and properties of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase. J Biol Chem. 1966 Jul 25;241(14):3365–3372. [PubMed] [Google Scholar]
  13. Jensen R. A., Nester E. W. Regulatory enzymes of aromatic amino acid biosynthesis in Bacillus subtilis. II. The enzymology of feedback inhibition of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase. J Biol Chem. 1966 Jul 25;241(14):3373–3380. [PubMed] [Google Scholar]
  14. Krieg R. E., Lockhart W. R. Classification of enterobacteria based on overall similarity. J Bacteriol. 1966 Nov;92(5):1275–1280. doi: 10.1128/jb.92.5.1275-1280.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Larkin J. M., Stokes J. L. Isolation of psychrophilic species of Bacillus. J Bacteriol. 1966 May;91(5):1667–1671. doi: 10.1128/jb.91.5.1667-1671.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Lim P. G., Mateles R. I. Tryptophan- and indole-excreting prototrophic mutant of Escherichia coli. J Bacteriol. 1964 May;87(5):1051–1055. doi: 10.1128/jb.87.5.1051-1055.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Mandel M., Weeks O. B., Colwell R. R. Deoxyribonucleic acid base composition of Pseudomonas piscicida. J Bacteriol. 1965 Nov;90(5):1492–1493. doi: 10.1128/jb.90.5.1492-1493.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Marmur J., Seaman E., Levine J. INTERSPECIFIC TRANSFORMATION IN BACILLUS. J Bacteriol. 1963 Feb;85(2):461–467. doi: 10.1128/jb.85.2.461-467.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Nester E. W., Jensen R. A. Control of aromatic acid biosynthesis in Bacillus subtilis: sequenial feedback inhibition. J Bacteriol. 1966 Apr;91(4):1594–1598. doi: 10.1128/jb.91.4.1594-1598.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. ROGOSA M. THE GENUS VEILLONELLA. I. GENERAL CULTURAL, ECOLOGICAL, AND BIOCHEMICAL CONSIDERATIONS. J Bacteriol. 1964 Jan;87:162–170. doi: 10.1128/jb.87.1.162-170.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. SMITH L. C., RAVEL J. M., LAX S. R., SHIVE W. The control of 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthesis by phenylalanine and tyrosine. J Biol Chem. 1962 Nov;237:3566–3570. [PubMed] [Google Scholar]
  22. STADTMAN E. R. Symptosium on multiple forms of enzymes and control mechanisms. II. Enzyme multiplicity and function in the regulation of divergent metabolic pathways. Bacteriol Rev. 1963 Jun;27:170–181. doi: 10.1128/br.27.2.170-181.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Spizizen J. TRANSFORMATION OF BIOCHEMICALLY DEFICIENT STRAINS OF BACILLUS SUBTILIS BY DEOXYRIBONUCLEATE. Proc Natl Acad Sci U S A. 1958 Oct 15;44(10):1072–1078. doi: 10.1073/pnas.44.10.1072. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Stadtman E. R. Allosteric regulation of enzyme activity. Adv Enzymol Relat Areas Mol Biol. 1966;28:41–154. doi: 10.1002/9780470122730.ch2. [DOI] [PubMed] [Google Scholar]
  25. Stanier R. Y., Palleroni N. J., Doudoroff M. The aerobic pseudomonads: a taxonomic study. J Gen Microbiol. 1966 May;43(2):159–271. doi: 10.1099/00221287-43-2-159. [DOI] [PubMed] [Google Scholar]
  26. Udaka S. Pathway-specific pattern of control of arginine biosynthesis in bacteria. J Bacteriol. 1966 Feb;91(2):617–621. doi: 10.1128/jb.91.2.617-621.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES