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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Bioessays. 2009 Feb;31(2):139–152. doi: 10.1002/bies.200800123

Figure 4. Pancreatic cell lineages.

Figure 4

A simplified summary of transcription factors identified for mouse and zebrafish pancreatic cell differentiation. Lineages are based on mouse data. Green indicates that a zebrafish homolog has been identified in the pancreas (see Table 1 for more details). Function of a particular transcription factor is not necessarily conserved between mouse and zebrafish. Gray indicates mouse pancreatic transcription factors that have not been identified in the zebrafish pancreas. Pancreatic Polypeptide-expressing cells (PP-cells) have not been identified in the zebrafish pancreas, although immunostaining with a rabbit PP antibody has revealed immunopositive cells in the intestine(116).