Skip to main content
PMC home page
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1964 Jul;88(1):20–24. doi: 10.1128/jb.88.1.20-24.1964

AMINO ACID ACCUMULATION IN ETHIONINE-RESISTANT SACCHAROMYCES CEREVISIAE1

W A Sorsoli a, K D Spence a, L W Parks a
PMCID: PMC277250  PMID: 14197889

Abstract

Sorsoli, W. A. (Oregon State University, Corvallis), K. D. Spence, and L. W. Parks. Amino acid accumulation in ethionine-resistant Saccharomyces cerevisiae. J. Bacteriol. 88:20–24. 1964.—Recessive ethionine-resistant strains of Saccharomyces cerevisiae possess a genetic lesion affecting the concentration of amino acids nonspecifically in the expandable pool of the organism. This area, which may be linked to a methionine gene, is highly mutable and accounts for resistance to certain amino acid analogues. Other mutations result in ethionine resistance by a mechanism unrelated to the amino acid uptake system.

Full text

PDF
20

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. COWIE D. B., McCLURE F. T. Metabolic pools and the synthesis of macromolecules. Biochim Biophys Acta. 1959 Jan;31(1):236–245. doi: 10.1016/0006-3002(59)90460-3. [DOI] [PubMed] [Google Scholar]
  2. HALVORSON H. O., COHEN G. N. Incorporation des amino-acides endogènes et exogènes dans les protéines de la levure. Ann Inst Pasteur (Paris) 1958 Jul;95(1):73–87. [PubMed] [Google Scholar]
  3. HALVORSON H. O., SPIEGELMAN S. The inhibition of enzyme formation by amino acid analogues. J Bacteriol. 1952 Aug;64(2):207–221. doi: 10.1128/jb.64.2.207-221.1952. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Hawthorne D C. The Use of Linear Asci for Chromosome Mapping in Saccharomyces. Genetics. 1955 Jul;40(4):511–518. doi: 10.1093/genetics/40.4.511. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. JOHNSTON J. R., MORTIMER R. K. Use of snail digestive juice in isolation of yeast spore tetrads. J Bacteriol. 1959 Aug;78:292–292. doi: 10.1128/jb.78.2.292-292.1959. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. KEMPNER E. S., COWIE D. B. Metabolic pools and the utilization of amino acid analogs for protein synthesis. Biochim Biophys Acta. 1960 Aug 26;42:401–408. doi: 10.1016/0006-3002(60)90817-9. [DOI] [PubMed] [Google Scholar]
  7. MAW G. A. The uptake of some sulphur-containing amino acids by a brewer's yeast. J Gen Microbiol. 1963 May;31:247–259. doi: 10.1099/00221287-31-2-247. [DOI] [PubMed] [Google Scholar]
  8. PIGG C. J., SORSOLI W. A., PARKS L. W. INDUCTION OF THE METHIONINE-ACTIVATING ENZYME IN SACCHAROMYCES CEREVISIAE. J Bacteriol. 1964 Apr;87:920–923. doi: 10.1128/jb.87.4.920-923.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. PIGG C. J., SPENCE K. D., PARKS L. W. Methionine biosynthesis in yeast. Arch Biochem Biophys. 1962 Jun;97:491–496. doi: 10.1016/0003-9861(62)90112-1. [DOI] [PubMed] [Google Scholar]
  10. RIGGS T. R., COYNE B., CHRISTENSEN H. N. Intensification of the cellular accumulation of amino acids by pyridoxal. Biochim Biophys Acta. 1953 Jun;11(2):303–304. doi: 10.1016/0006-3002(53)90041-9. [DOI] [PubMed] [Google Scholar]
  11. SCHLENK F., DEPALMA R. E. The formation of S-adenosylmethionine in yeast. J Biol Chem. 1957 Dec;229(2):1037–1050. [PubMed] [Google Scholar]
  12. STARR P. R., PARKS L. W. Some factors affecting sterol formation in Saccharomyces cerevisiae. J Bacteriol. 1962 May;83:1042–1046. doi: 10.1128/jb.83.5.1042-1046.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES