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. 1965 Apr;89(4):1097–1100. doi: 10.1128/jb.89.4.1097-1100.1965

Location and Regeneration of Enterovirus Receptors of HeLa Cells1

Ihor Zajac a, Richard L Crowell a,2
PMCID: PMC277602  PMID: 14279119

Abstract

Zajac, Ihor (Hahnemann Medical College, Philadelphia, Pa.), and Richard L. Crowell. Location and regeneration of enterovirus receptors of HeLa cells. J. Bacteriol. 89:1097–1100. 1965.—Treatment of live HeLa cells with chymotrypsin or trypsin completely inactivated the viral receptors for coxsackievirus B3 and poliovirus T1, respectively. Enzyme-treated cells regained their enterovirus receptor activity after incubation in culture medium. The existence of intracellular receptors for virus could not be demonstrated when live HeLa cells were treated with enzyme prior to disruption and fractionation. These results suggested that receptors for enteroviruses are limited to the cell surface.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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