Abstract
Garen, A. (University of Pennsylvania, Philadelphia) and H. Echols. Properties of two regulating genes for alkaline phosphatase. J. Bacteriol. 83:297–300. 1962.—A constitutive mutation in one of the two regulating genes for alkaline phosphatase has two effects on the synthesis of the enzyme: repression of synthesis is blocked, and the cell's capacity to produce the enzyme is reduced. The behavior of this type of mutation has been studied in heterozygotes. The results suggest that the product of this regulating gene functions as an inducer as well as a repressor.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ECHOLS H., GAREN A., GAREN S., TORRIANI A. Genetic control of repression of alkaline phosphatase in E. coli. J Mol Biol. 1961 Aug;3:425–438. doi: 10.1016/s0022-2836(61)80055-7. [DOI] [PubMed] [Google Scholar]
- LEVINTHAL C. Genetic and chemical studies with alkaline phosphatase of E. coli. Brookhaven Symp Biol. 1959 Nov;12:76–85. [PubMed] [Google Scholar]
- TORRIANI A. Influence of inorganic phosphate in the formation of phosphatases by Escherichia coli. Biochim Biophys Acta. 1960 Mar 11;38:460–469. doi: 10.1016/0006-3002(60)91281-6. [DOI] [PubMed] [Google Scholar]