Table 2.
Pathogen | Resistant to | Rooled RD (RP%) of all SARI-ICUs 01/2001–12/2004 | RD from 34 SARI ICUs providing resistance data from 2001 to 2004 | |||||||
---|---|---|---|---|---|---|---|---|---|---|
No tested | Pooled mean | 25% percentile | Median | 75% percentile | No ICUs** in analysis | Year 2001 median RD | Year 2004 median RD | No. of ICUs with an increase/decrease/no change of RD from 2001 to 2004 | ||
S. aureus | MethiciLLin | 12,238 | 4.4 (21.5%) | 1.92 (12.0%) | 3.34 (21.2%) | 4.8 (32.1%) | 30 | 2.7 | 3.7 | 18/12/0 |
E. faecalis | Vancomycin | 5,371 | 0.0 (0.1%) | 0.0 (0%) | 0.0 | 0.0 | 27 | 0 | 0 | 0/1/26 |
E. faecium | Vancomycin | 1,945 | 0.1 (2.6%) | 0.0 (0%) | 0.0 | 0.1 (3.3%) | 11 | 0 | 0 | 2/3/6 |
K. pneumoniae | Third gen. cephalosporins | 3,205 | 0.4 (7.5%) | 0.0 (0%) | 0.1 (2.0%) | 0.3 (6.5%)) | 20 | 0 | 0.2 | 9/3/8 |
E. coli | Third gen. cephalosporins | 8,110 | 0.3 (2.3%) | 0.0 (0%) | 0.2 (1.7%) | 0.5 (3.5%) | 27 | 0 | 0.2 | 14/6/7* |
Ciprofloxacin | 7,152 | 1.5 (12.3%) | 0.5 (8.3%) | 1.3 (12.0%) | 2.0 (16.6%) | 27 | 1.1 | 1.8 | 20/5/2* | |
P. aeruginosa | Imipenem | 4,442 | 1.7 (23.2%) | 0.4 (8.4%) | 1.1 (18.6%) | 2.4 (26.6%) | 21 | 2.0 | 1.1 | 5/16/0 |
Ceftazidime | 5,005 | 1.3 (15.6%) | 0.4 (6.5%) | 1.0 (11.1%) | 2.0 (20.5%) | 26 | 0.6 | 1.1 | 14/12/0 | |
Ciprofloxacin | 5,009 | 1.5 (17.6%) | 0.5 (8.6%) | 1.2 (15.4%) | 2.2 (26.2%) | 26 | 1.2 | 1.0 | 10/14/2 | |
Piperacillin-tazobactam | 4,058 | 1.5 (22.0%) | 0.3 (8.7%) | 0.0 (15.7%) | 3.5 (36.7%) | 21 | 1.6 | 1.4 | 9/12/0 |
“Resistant to third generation cephalosporins” i.e. cefotaxim or ceftiaxon or ceftazidime; *if p-value < 0.05 by Wilcoxon signed-rank test for paired samples 2001 vs 2004; ** ICUs with on at least ten isolates tested per antimicrobial/pathogen per year