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. 1962 Dec;84(6):1282–1286. doi: 10.1128/jb.84.6.1282-1286.1962

GROWTH CHARACTERISTICS OF MYCOBACTERIUM AVIUM AND GROUP III NONPHOTOCHROMOGENIC MYCOBACTERIA IN HELA CELLS1

Edwin A Brosbe a, Paul T Sugihara a, C Richard Smith a
PMCID: PMC278059  PMID: 14015826

Abstract

Brosbe, Edwin A. (Veterans Administration Hospital, Long Beach, Calif.), Paul T. Sugihara, and C. Richard Smith. Growth characteristics of Mycobacterium avium (avian) to group III nonphotochromogenic mycobacteria in HeLa cells. J. Bacteriol. 84:1282–1286. 1962.—The close relationship of Mycobacterium avium (avian) to group III nonphotochromogenic (Battey) strains of mycobacteria stimulated interest in their behavior in HeLa cells. In general, the avian strains grew more slowly than the Battey strains; 10 of 17 avian and 3 of 12 Battey strains required more than 7 days to exhibit abundant intracellular growth. Branching filaments were observed with variable frequency in all of the strains studied. Branching occurred at right angles, and was seen more often with the Battey strains and the avian strains isolated from swine. These observations indicate that the growth rate and growth pattern of avian and Battey mycobacteria in HeLa cells are not sufficiently specific to facilitate distinguishing the two species from each other.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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