COSTS |
|
|
|
|
Influenza Vaccine ($US) |
15.00 |
- |
- |
[23] |
Vaccine Administration ($US) |
5.00 |
- |
- |
Estimate |
Anti-Viral medication: Oseltamivir ($US) |
99.32 |
77.32 |
121.32 |
[23] |
Influenza Treatment: |
|
|
|
|
Over the Counter Medications ($US) |
15.61 |
10.30 |
20.91 |
[23] |
Outpatient Visit ($US) |
151.38 |
114.94 |
187.81 |
[24] |
Productivity Loss for Outpatient Visit ($US) |
64.08 |
54.00 |
74.16 |
[25] |
Hospitalization ($US), 65-84 years old |
4723 |
4382 |
5064 |
[26] |
Hospitalization ($US), >85 years old |
5146 |
5406 |
5886 |
[26] |
Death in Hospital ($US) |
5,000 |
- |
- |
[27] |
Treatment of Vaccine Side Effects ($US) |
0.76 |
0.68 |
3.82 |
[28] |
DURATIONS |
|
|
|
|
Influenza (days) |
7 |
- |
- |
[27, 29, 30] |
Clinic Visit (hours) |
4 |
- |
- |
[27, 29, 30] |
UTILITIES |
|
|
|
|
One Year of Life for Older Adult (QALY) |
0.84 |
- |
- |
[10] |
Utility/Day |
|
|
|
|
Influenza no Hospitalization (QALY) |
0.65 |
0.49 |
0.81 |
[11, 31] |
Influenza with Hospitalization (QALY) |
0.50 |
0.38 |
0.63 |
[11, 31] |
Vaccine Side Effects (QALY) |
0.95 |
0.71 |
1.00 |
[11] |
PROBABILITIES |
|
|
|
|
Clinical Outcomes without Vaccination |
|
|
|
|
Influenza throughout the Year |
0.125 |
0.05 |
0.20 |
[14] |
Clinic Visit Given Influenza |
0.40 |
- |
- |
[14] |
Hospitalization Given Influenza |
0.04 |
0.01 |
0.07 |
[14] |
Clinical Outcomes with Vaccination |
|
|
|
|
Reduction in Hospitalization |
0.565 |
0.45 |
0.68 |
[14] |
Reduction in Mortality |
0.21 |
0 |
0.42 |
[14] |
Side Effects |
0.05 |
- |
- |
[14] |
Decrease in Attack Rate from Earlier Vaccination |
0.00 |
0.00 |
0.25 |
[13, 14] |