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. 1963 Jun;85(6):1217–1220. doi: 10.1128/jb.85.6.1217-1220.1963

ANTAGONISM OF d-CYCLOSERINE INHIBITION OF MYCOBACTERIAL GROWTH BY d-ALANINE

Walter A Zygmunt 1
PMCID: PMC278322  PMID: 14047211

Abstract

Zygmunt, Walter A. (Mead Johnson & Co., Evansville, Ind.). Antagonism of d-cycloserine inhibition of mycobacterial growth by d-alanine. J. Bacteriol. 85:1217–1220. 1963.—Reversal of the antimycobacterial activity of d-4-amino-3-isoxazolidinone (d-cycloserine) by alanine in two species of mycobacteria actively growing on chemically defined media was compared. In both instances, d-alanine was the most effective reversal agent. The specificity with which the d isomer reversed the antimycobacterial activity of d-cycloserine was more pronounced than that observed with other species of bacteria. Mycobactin, a growth factor for certain mycobacteria, showed no reversal activity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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