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. 1963 Sep;86(3):363–369. doi: 10.1128/jb.86.3.363-369.1963

COAGULASE-NEGATIVE MUTANTS OF STAPHYLOCOCCUS AUREUS: GENETIC STUDIES

Ruth Z Korman 1
PMCID: PMC278444  PMID: 14066411

Abstract

Korman, Ruth Z. (Cornell University, Ithaca, N.Y.). Coagulase-negative mutants of Staphylococcus aureus: genetic studies. J. Bacteriol. 86:363–369. 1963.—The behavior in mutation and transduction of pleiotropic coagulase-negative mutants of Staphylococcus aureus PS 53 (NCTC 8511) was analyzed. Coagulase-positive colonies were recovered, as well as a novel phenotype resistant to some cell-wall inhibitors and differing in sugar fermentation pattern. The hypothesis that the coagulase-negative strains differ from the original propagating strain in the structure or organization of the cell wall is discussed.

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Selected References

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  1. BLAIR J. E. What is a Staphylococcus? Bacteriol Rev. 1962 Dec;26:375–381. doi: 10.1128/br.26.4.375-381.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. COLLINS A. M., McDONALD S. Transduction of tetracycline resistance in Staphylococci. J Pathol Bacteriol. 1962 Apr;83:399–404. doi: 10.1002/path.1700830209. [DOI] [PubMed] [Google Scholar]
  3. COMTOIS R. D. Lysogeny in a coagulase-negative Staphylococcus. Can J Microbiol. 1962 Apr;8:201–211. doi: 10.1139/m62-026. [DOI] [PubMed] [Google Scholar]
  4. DENEKE A., BLOBEL H. Fibrinogen media for studies on staphylococci. J Bacteriol. 1962 Mar;83:533–537. doi: 10.1128/jb.83.3.533-537.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Dowell C. E., Rosenblum E. D. SEROLOGY AND TRANSDUCTION IN STAPHYLOCOCCAL PHAGE. J Bacteriol. 1962 Nov;84(5):1071–1075. doi: 10.1128/jb.84.5.1071-1075.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. EDGAR J. B., STOCKER B. A. Metabolic and genetic investigations of nutritionally exacting strains of Staphylococcus pyogenes. Nature. 1961 Sep 9;191:1121–1122. doi: 10.1038/1911121a0. [DOI] [PubMed] [Google Scholar]
  7. HAUKENES G., ELLWOOD D. C., BADDILEY J., OEDING P. Serological cross-reactivity between polysaccharide A and teichoic acid of Staphylococcus aureus. Biochim Biophys Acta. 1961 Oct 28;53:425–426. doi: 10.1016/0006-3002(61)90461-9. [DOI] [PubMed] [Google Scholar]
  8. KORMAN R. Z., BERMAN D. T. Genetic transduction with staphylophage. J Bacteriol. 1962 Aug;84:228–236. doi: 10.1128/jb.84.2.228-236.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. KORMAN R. Z., BERMAN D. T. Medium for the differentiation of acid producing colonies of staphylococci. J Bacteriol. 1958 Oct;76(4):454–455. doi: 10.1128/jb.76.4.454-455.1958. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. KORMAN R. Z. Transduction of a pleiotropic carbohydrate locus in Staphylococcus aureus. J Bacteriol. 1962 Dec;84:1338–1339. doi: 10.1128/jb.84.6.1338-1339.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Morse M L, Lederberg E M, Lederberg J. Transductional Heterogenotes in Escherichia Coli. Genetics. 1956 Sep;41(5):758–779. doi: 10.1093/genetics/41.5.758. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Morse M. L. TRANSDUCTION BY STAPHYLOCOCCAL BACTERIOPHAGE. Proc Natl Acad Sci U S A. 1959 May;45(5):722–727. doi: 10.1073/pnas.45.5.722. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. NATHENSON S. G., STROMINGER J. L. Enzymatic synthesis and immunochemistry of N-acetylglucosaminylribitol linkages in the teichoic acids of Staphylococcus aureus stains. J Biol Chem. 1962 Dec;237:3839–3841. [PubMed] [Google Scholar]
  14. PATTEE P. A., BALDWIN J. N. Transduction of resistance to some macrolide antibiotics in Staphylococcus aureus. J Bacteriol. 1962 Nov;84:1049–1055. doi: 10.1128/jb.84.5.1049-1055.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. RITZ H. L., BALDWIN J. N. A transduction analysis of complex loci governing the synthesis of tryptophan by Staphylococcus aureus. Proc Soc Exp Biol Med. 1962 Aug-Sep;110:667–671. doi: 10.3181/00379727-110-27611. [DOI] [PubMed] [Google Scholar]
  16. RITZ H. L., BALDWIN J. N. Transduction of capacity to produce staphylococcal penicillinase. Proc Soc Exp Biol Med. 1961 Jul;107:678–680. doi: 10.3181/00379727-107-26726. [DOI] [PubMed] [Google Scholar]
  17. STROMINGER J. L. Biosynthesis of bacterial cell walls. Fed Proc. 1962 Jan-Feb;21:134–143. [PubMed] [Google Scholar]
  18. ZEBOVITZ E., EVANS J. B., NIVEN C. F., Jr Tellurite-glycine agar: a selective plating medium for the quantitative detection of coagulase-positive staphylococci. J Bacteriol. 1955 Dec;70(6):686–690. doi: 10.1128/jb.70.6.686-690.1955. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. ZINDER N. D., LEDERBERG J. Genetic exchange in Salmonella. J Bacteriol. 1952 Nov;64(5):679–699. doi: 10.1128/jb.64.5.679-699.1952. [DOI] [PMC free article] [PubMed] [Google Scholar]

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