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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Neurotoxicology. 2009 Sep 6;30(6):898–914. doi: 10.1016/j.neuro.2009.08.011

Figure 8. Permutation analysis of the GxE-eQTL data.

Figure 8

a, The experimental GxE-eQTL data are plotted with eQTL location (x-axis) and number of probesets with eQTL at the corresponding location (y-axis) (intensity = G + E + GXE + error). The hotspot with 812 probesets at 50DF is indicated (50F). b, The GxE-eQTL results of 100 permutations is plotted (intensity = G + E + GXE + error). c, The rank order of GxE-eQTL hotspots (x-axis) in the 100 permutations is plotted versus the number of genes with eQTL in the largest transband (y-axis). The experimental data (real data) has 819 probesets in the largest transband. d, The rank order of the number of GxE-eQTL in the 100 permutations is plotted. Notice that most (94%) of the permutations have larger transbands than the experimental data (arrow).