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. Author manuscript; available in PMC: 2010 Nov 12.
Published in final edited form as: Neuron. 2009 Nov 12;64(3):367–380. doi: 10.1016/j.neuron.2009.09.043

Figure 5.

Figure 5

Rescue of Drosophila Complexin null mutants with murine Cplx and dmCplx. (A) Representative traces of evoked EJPs. The arrows represent stimulations. (B) Representative traces of mEJPs. (C and D) Summary data for amplitude of EJP evoked by single action potentials (C) and mEJP frequency (D). #, note that the mEJP frequency of null is underestimated due to the overlap of individual mEJPs. Simulation indicates that the true frequency is probably higher than 50 Hz (Supplemental results and Figure S10). Genotypes: control (C155-GAL4/Y), null (C155-GAL4/Y; dmCplxSH1/dmCplxSH1), dmCplx rescue (C155-GAL4/Y; UAS-dmCplx/+; dmCplxSH1/dmCplxSH1), CplxI rescue (C155-GAL4/Y; UAS-CplxI/+; dmCplxSH1/dmCplxSH1), and CplxIII rescue (C155-GAL4/Y; UAS-CplxIII/+; dmCplxSH1/dmCplxSH1). For transgenic rescue experiments, multiple lines show similar results and data are pooled together. Data are expressed as mean ± SEM. **, P < 0.001; ***, P < 0.0001 compared to control. The numbers of neuromuscular junctions analyzed are shown above the bars.